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Literature summary extracted from

  • Kruse, T.; Levisson, M.; de Vos, W.M.; Smidt, H.
    vanI a novel D-Ala-D-Lac vancomycin resistance gene cluster found in Desulfitobacterium hafniense (2014), Microb. Biotechnol., 7, 456-466 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.2.1 D-alanine + (R)-lactate + ATP Desulfitobacterium hafniense
-
 D-alanyl-(R)-lactate + ADP + phosphate
-
 ?
6.1.2.1 D-alanine + (R)-lactate + ATP Desulfitobacterium hafniense Y51
-
 D-alanyl-(R)-lactate + ADP + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.2.1 Desulfitobacterium hafniense
-
-
-
6.1.2.1 Desulfitobacterium hafniense Y51
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.2.1 D-alanine + (R)-lactate + ATP
-
 Desulfitobacterium hafniense D-alanyl-(R)-lactate + ADP + phosphate
-
 ?
6.1.2.1 D-alanine + (R)-lactate + ATP
-
 Desulfitobacterium hafniense Y51 D-alanyl-(R)-lactate + ADP + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.2.1 D-Ala-D-Lac ligase
-
 Desulfitobacterium hafniense
6.1.2.1 VanI
-
 Desulfitobacterium hafniense

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.2.1 ATP
-
 Desulfitobacterium hafniense