Any feedback?
Literature summary extracted from
- Elucidating vital drug targets of Salmonella enterica utilizing the bioinformatic approach (2016), J. Pharm. Sci. Res., 8, 71-78 .
No PubMed abstract available
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 1.17.1.1 | drug development | the enzyme is a drug target | Salmonella enterica subsp. enterica serovar Typhimurium |
| 1.17.1.1 | drug development | the enzyme is a drug target | Salmonella enterica |
| 1.17.1.1 | drug development | the enzyme is a drug target | Salmonella enterica subsp. enterica serovar Gallinarum |
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.17.1.1 | gene ascD, sequence analysis and comparisons | Salmonella enterica subsp. enterica serovar Typhimurium |
| 1.17.1.1 | gene rfbH, sequence analysis and comparisons | Salmonella enterica subsp. enterica serovar Gallinarum |
| 1.17.1.1 | sequence analysis and comparisons | Salmonella enterica |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.17.1.1 | ZINC00020252 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum |  |
| 1.17.1.1 | ZINC00020252 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC00057147 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC00057147 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC00057347 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC00057347 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC00057358 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC00057358 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC03201893 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC03794794 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC03794794 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC03830609 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC03830609 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC03831425 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC03831426 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC03831427 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC03831428 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC06507052 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC06507052 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC08551105 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC08551106 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC08551107 | inhibits CDP-4-dehydro-6-deoxyglucose reductase | Salmonella enterica | |
| 1.17.1.1 | ZINC12503116 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC12503116 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | ZINC20444132 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | ZINC20444132 | inhibits CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | Salmonella enterica subsp. enterica serovar Typhimurium | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | Salmonella enterica subsp. enterica serovar Typhimurium | - |
CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | Salmonella enterica | - |
CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
r | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | Salmonella enterica subsp. enterica serovar Gallinarum | - |
CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | Salmonella enterica subsp. enterica serovar Gallinarum SG9 | - |
CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | Salmonella enterica subsp. enterica serovar Typhimurium DT104 | - |
CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.17.1.1 | Salmonella enterica | - |
- |
- |
| 1.17.1.1 | Salmonella enterica subsp. enterica serovar Gallinarum | - |
gene rfbH | - |
| 1.17.1.1 | Salmonella enterica subsp. enterica serovar Gallinarum SG9 | - |
gene rfbH | - |
| 1.17.1.1 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
gene ascD | - |
| 1.17.1.1 | Salmonella enterica subsp. enterica serovar Typhimurium DT104 | - |
gene ascD | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
r | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
r | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Gallinarum | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Gallinarum | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
r | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Gallinarum SG9 | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Gallinarum SG9 | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
r | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium DT104 | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
? | |
| 1.17.1.1 | CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD+ + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium DT104 | CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+ | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.17.1.1 | More | enzyme structure prediction, model | Salmonella enterica subsp. enterica serovar Typhimurium |
| 1.17.1.1 | More | enzyme structure prediction, model | Salmonella enterica |
| 1.17.1.1 | More | enzyme structure prediction, model | Salmonella enterica subsp. enterica serovar Gallinarum |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.17.1.1 | ascD | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
| 1.17.1.1 | CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
| 1.17.1.1 | CDP-6-deoxy-D-xylo-4-hexulose-3-dehydrase | - |
Salmonella enterica subsp. enterica serovar Gallinarum |
| 1.17.1.1 | rfbH | - |
Salmonella enterica subsp. enterica serovar Gallinarum |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.17.1.1 | NAD+ | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | NAD+ | - |
Salmonella enterica | |
| 1.17.1.1 | NAD+ | - |
Salmonella enterica subsp. enterica serovar Gallinarum | |
| 1.17.1.1 | NADH | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| 1.17.1.1 | NADH | - |
Salmonella enterica | |
| 1.17.1.1 | NADH | - |
Salmonella enterica subsp. enterica serovar Gallinarum | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
