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Literature summary extracted from

  • Priya, R.; Sneha, P.; Rivera Madrid, R.; Doss, C.G.P.; Singh, P.; Siva, R.
    Molecular modeling and dynamic simulation of Arabidopsis thaliana carotenoid cleavage dioxygenase gene a comparison with Bixa orellana and Crocus sativus (2017), J. Cell. Biochem., 118, 2712-2721 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.13.11.68 gene ccd7, sequence comparisons Arabidopsis thaliana
1.13.11.70 gene ccd8, sequence comparisons Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.68 9-cis-beta-carotene + O2 Arabidopsis thaliana
-
 9-cis-10'-apo-beta-carotenal + beta-ionone
-
 ?
1.13.11.69 9-cis-10'-apo-beta-carotenal + 2 O2 Arabidopsis thaliana
-
 carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal
-
 ?
1.13.11.70 all-trans-10'-apo-beta-carotenal + O2 Arabidopsis thaliana
-
 13-apo-beta-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.68 Arabidopsis thaliana Q7XJM2
-
-
1.13.11.69 Arabidopsis thaliana Q8VY26
-
-
1.13.11.70 Arabidopsis thaliana Q8VY26
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.68 9-cis-beta-carotene + O2
-
 Arabidopsis thaliana 9-cis-10'-apo-beta-carotenal + beta-ionone
-
 ?
1.13.11.68 additional information AtCCD7 cleaves asymmetrically at the 9, 10, and 9', 10' bonds Arabidopsis thaliana ?
-
 ?
1.13.11.69 9-cis-10'-apo-beta-carotenal + 2 O2
-
 Arabidopsis thaliana carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal
-
 ?
1.13.11.70 all-trans-10'-apo-beta-carotenal + O2
-
 Arabidopsis thaliana 13-apo-beta-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.68 carotenoid cleavage dioxygenase
-
 Arabidopsis thaliana
1.13.11.68 CCD7
-
 Arabidopsis thaliana
1.13.11.69 carotenoid cleavage dioxygenase 8
-
 Arabidopsis thaliana
1.13.11.69 CCD8
-
 Arabidopsis thaliana
1.13.11.70 carotenoid cleavage dioxygenase
-
 Arabidopsis thaliana
1.13.11.70 CCD8
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
1.13.11.68 evolution occurrence of duplication in CCD4 genes that evolved into two new genes CCD7 and CCD8, EC 1.13.11.70. The site-specific profile and coefficient of type-I functional divergences reveals critical amino acid residues, leading to subgroup-specific functional evolution after their phylogenetic diversification Arabidopsis thaliana
1.13.11.68 additional information in silico analysis, structure homology modeling, molecular modeling, dynamic simulation and structure comparisons of Arabidopsis thaliana carotenoid cleavage dioxygenases, overview Arabidopsis thaliana
1.13.11.70 evolution occurrence of duplication in CCD4 genes that evolved into two new genes CCD7, EC 1.13.11.68, and CCD8. The site-specific profile and coefficient of type-I functional divergences reveals critical amino acid residues, leading to subgroup-specific functional evolution after their phylogenetic diversification Arabidopsis thaliana
1.13.11.70 additional information in silico analysis, structure homology modeling, molecular modeling, dynamic simulation and structure comparisons of Arabidopsis thaliana carotenoid cleavage dioxygenases, overview Arabidopsis thaliana