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Literature summary extracted from

  • Westcott, K.R.; Hill, R.L.
    Reconstitution of a porcine submaxillary gland beta-D-galactoside alpha 2-3 sialyltransferase into liposomes (1985), J. Biol. Chem., 260, 13116-13121 .
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.3.4 lysophosphatidylcholine C16-18 acyl derivatives of lysophosphatidylcholine stimulate the activity of enzyme form A more extensively than the C14 acyl derivative, and the C12 acyl derivative is without effect on enzyme form A Sus scrofa
2.4.3.4 phospholipid/octylglucoside liposomes incorporation into phospholipid/octylglucoside liposomes activates enzyme form A Sus scrofa
2.4.3.4 Triton X-100 stimulates activity of enzyme form A. Enzyme form B is fully active in absence of detergents. Detergents stimulate the activity of enzyme form A by lowering the KD and KM of CMP-N-acetylneuraminate and increasing the Vmax of the reaction Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.3.4 lysophosphatidylglycerol inhibition of enzyme form A and B Sus scrofa
2.4.3.4 lysophosphatidylserine inhibition of enzyme form A Sus scrofa
2.4.3.4 octyl-D-glucoside inhibition of enzyme form A and B Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.4 Golgi apparatus
-
Sus scrofa 5794
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.3.4 44000
-
enzyme form B Sus scrofa
2.4.3.4 49000
-
enzyme form A Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.4 Sus scrofa Q02745
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.3.4
-
Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.4 submandibular gland
-
Sus scrofa
-