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Literature summary extracted from

  • Yi, H.; Lee, H.; Cho, K.H.; Kim, H.S.
    Mutations in MetG (methionyl-tRNA synthetase) and TrmD [tRNA (guanine-N1)-methyltransferase] conferring meropenem tolerance in Burkholderia thailandensis (2018), J. Antimicrob. Chemother., 73, 332-338 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
6.1.1.10 F316S the mutant exhibits a significantly reduced growth rate compared with the wild type Burkholderia thailandensis
6.1.1.10 F501L the mutant exhibits a significantly reduced growth rate compared with the wild type Burkholderia thailandensis
6.1.1.10 L216P the mutant exhibits a significantly reduced growth rate compared with the wild type Burkholderia thailandensis
6.1.1.10 P27S the mutant exhibits a significantly reduced growth rate compared with the wild type Burkholderia thailandensis
6.1.1.10 R424P the mutant exhibits a significantly reduced growth rate compared with the wild type Burkholderia thailandensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.10 ATP + L-methionine + tRNAMet Burkholderia thailandensis
-
 AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.10 Burkholderia thailandensis Q2T087
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.10 ATP + L-methionine + tRNAMet
-
 Burkholderia thailandensis AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.10 MetG
-
 Burkholderia thailandensis
6.1.1.10 methionyl-tRNA synthetase
-
 Burkholderia thailandensis

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.10 ATP
-
 Burkholderia thailandensis