EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.1 | 1-pentanoyl-3-(2,3-dichlorophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(2,4,6-trimethylphenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(2,4-dinitrophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(2,6-dibromo-4-fluorophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(3-nitrophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(4-bromo-2-fluorophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(4-bromophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(4-chlorophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(4-methoxyphenyl)thiourea | noncompetitive inhibition, docking interaction analysis between 1-pentanoyl-3-(4-methoxyphenyl)thiourea and mushroom tyrosinase | Agaricus bisporus | |
1.14.18.1 | 1-pentanoyl-3-(4-nitrophenyl)thiourea | - |
Agaricus bisporus | |
1.14.18.1 | kojic acid | - |
Agaricus bisporus | |
1.14.18.1 | additional information | design, synthesis, kinetic mechanism, and molecular docking studies of 1-pentanoyl-3-arylthioureas as inhibitors of mushroom tyrosinase and free radical scavengers, structure activity relationships, overview | Agaricus bisporus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.18.1 | Agaricus bisporus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.18.1 | commercial preparation | - |
Agaricus bisporus | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.18.1 | mushroom tyrosinase | - |
Agaricus bisporus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.18.1 | 25 | - |
assay at | Agaricus bisporus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.18.1 | 6.8 | - |
assay at | Agaricus bisporus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.18.1 | additional information | - |
additional information | inhibition kinetics | Agaricus bisporus | |
1.14.18.1 | 0.0011 | 0.0016 | 1-pentanoyl-3-(4-methoxyphenyl)thiourea | pH 6.8, 25°C | Agaricus bisporus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.14.18.1 | 0.0016 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(4-methoxyphenyl)thiourea | |
1.14.18.1 | 0.0023 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(4-chlorophenyl)thiourea | |
1.14.18.1 | 0.0034 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(4-bromophenyl)thiourea | |
1.14.18.1 | 0.0065 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(4-bromo-2-fluorophenyl)thiourea | |
1.14.18.1 | 0.0078 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(2,3-dichlorophenyl)thiourea | |
1.14.18.1 | 0.008 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(4-nitrophenyl)thiourea | |
1.14.18.1 | 0.0101 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(2,4-dinitrophenyl)thiourea | |
1.14.18.1 | 0.0166 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(3-nitrophenyl)thiourea | |
1.14.18.1 | 0.0195 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(2,6-dibromo-4-fluorophenyl)thiourea | |
1.14.18.1 | 0.0197 | - |
pH 6.8, 25°C | Agaricus bisporus | 1-pentanoyl-3-(2,4,6-trimethylphenyl)thiourea |