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Literature summary extracted from

  • Giordanengo, V.; Bannwarth, S.; Laffont, C.; Van Miegem, V.; Harduin-Lepers, A.; Delannoy, P.; Lefebvre, J.C.
    Cloning and expression of cDNA for a human Gal(beta1-3)GalNAc alpha2,3-sialyltransferase from the CEM T-cell line (1997), Eur. J. Biochem., 247, 558-566 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.3.2 a soluble form of hST3Gal II is expressed in COS-7 cells Homo sapiens
2.4.3.2 expressed in COS-7 cells Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.3.2 0.46
-
 ganglioside GA1 pH 6.5, 37°C Homo sapiens
2.4.3.2 0.87
-
 ganglioside GM1a pH 6.5, 37°C Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.2 Homo sapiens Q16842
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.2 bone marrow
-
 Homo sapiens
-
2.4.3.2 heart highly expressed Homo sapiens
-
2.4.3.2 heart high expression Homo sapiens
-
2.4.3.2 liver highly expressed Homo sapiens
-
2.4.3.2 liver high expression Homo sapiens
-
2.4.3.2 lymph node
-
 Homo sapiens
-
2.4.3.2 lymphoid tissue high expression Homo sapiens
-
2.4.3.2 additional information not expressed in brain and kidney Homo sapiens
-
2.4.3.2 skeletal muscle highly expressed Homo sapiens
-
2.4.3.2 skeletal muscle high expression Homo sapiens
-
2.4.3.2 spleen
-
 Homo sapiens
-
2.4.3.2 thymus
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.2 CMP-N-acetyl-beta-neuraminate + benzyl beta-D-Gal-(1->3)-beta-D-GalNAc
-
 Homo sapiens CMP + benzyl alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + beta-D-Gal-(1->3)-beta-D-GalNAc
-
 Homo sapiens CMP + alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GalNAc
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GA1
-
 Homo sapiens CMP + ganglioside GM1b
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GD1b
-
 Homo sapiens CMP + ganglioside GT1b
-
 ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Homo sapiens CMP + ganglioside GD1a
-
 ?
2.4.3.2 additional information no transfer onto D-Gal-beta-(1->4)-D-GlcNAc, GalNAc-beta-(1->4)-D-GlcNAc or D-Gal-beta-(l->4)-D-Glc is detected Homo sapiens ?
-
 ?
2.4.3.2 additional information no transfer onto Galbeta-(1->4)-D-GlcNAc, GalNAc-beta-(1->4)-D-GlcNAc or Gal-beta-(1->4)-Glc is detected Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.2 hST3Gal II
-
 Homo sapiens
2.4.3.2 ST3Gal II
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.3.2 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.3.2 6.5
-
 assay at Homo sapiens