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Literature summary extracted from

  • Chu, S.; Wang, J.; Cheng, H.; Yang, Q.; Yu, D.
    Evolutionary study of the isoflavonoid pathway based on multiple copies analysis in soybean (2014), BMC Genet., 15, 76 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.87 Glycine max Q9SWR5
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.87 hairy root
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 Glycine max
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Synonyms

EC Number Synonyms Comment Organism
1.14.14.87 IFS2
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 Glycine max
1.14.14.87 isoflavone synthase 2
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 Glycine max

Expression

EC Number Organism Comment Expression
1.14.14.87 Glycine max the R2R3-type MYB transcription factor GmMYB29 is located in the nucleus and activates the IFS2 (isoflavone synthase 2) gene promoter. Overexpression and RNAi-mediated silencing of GmMYB29 in soybean hairy roots results in increased and decreased isoflavone content, respectively. 11 Natural GmMYB29 polymorphisms are significantly associated with isoflavone contents, and regulation of GmMYB29 expression partially contributes to a phenotypic variation observed after inhibition of GmMYB29 up

General Information

EC Number General Information Comment Organism
1.14.14.87 malfunction overexpression and RNAi-mediated silencing of GmMYB29 in soybean hairy roots resulted in increased and decreased isoflavone content, respectively. 11 Natural GmMYB29 polymorphisms are significantly associated with isoflavone contents, and regulation of GmMYB29 expression partially contributes to the observed phenotypic variation, the detected single nucleotide polymorphism is SNP AX-93910416, detected within the 5'-untranslated region of Glyma20g35180 (GmMYB29) Glycine max
1.14.14.87 metabolism the critical branch point enzymes chalcone synthase (CHS) and isoflavone synthase (IFS) lead substrates to the isoflavone synthesis branch and finally generate isoflavones and their derivatives, isoflavone regulation-related transcription factors, overview. Positive regulatory role of GmMYB29 in isoflavone biosynthesis Glycine max