Literature summary extracted from

Park, S.J.; Oh, Y.H.; Noh, W.; Kim, H.Y.; Shin, J.H.; Lee, E.G.; Lee, S.; David, Y.; Baylon, M.G.; Song, B.K.; Jegal, J.; Lee, S.Y.; Lee, S.H.
High-level conversion of L-lysine into 5-aminovalerate that can be used for nylon 6,5 synthesis (2014), Biotechnol. J., 9, 1322-1328 .

Application

EC Number	Application	Comment	Organism
1.13.12.2	synthesis	L-lysine is a potential feedstock for the production of bio-based precursors for engineering plastics. Usage of the enzyme in a microbial process for high-level conversion of L-lysine into 5-aminovalerate that can be used as a monomer in nylon 6,5 synthesis, method overview	Pseudomonas putida

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.13.12.2	gene davB, recombinant expression in Escherichia coli strain WL3110, coexpression with gene davA, encoding 5-aminovaleramidase	Pseudomonas putida

Protein Variants

EC Number	Protein Variants	Comment	Organism
1.13.12.2	additional information	Escherichia coli strain WL3110, coexpressing genes davB and davA, is used as whole-cell-catalyst for production of 5-aminovalerate from L-lysine, method optimization, overview	Pseudomonas putida

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.13.12.2	L-lysine + O2	Pseudomonas putida	-	5-aminopentanamide + CO2 + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.12.2	Pseudomonas putida	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.12.2	L-lysine + O2	-	Pseudomonas putida	5-aminopentanamide + CO2 + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.13.12.2	davB	-	Pseudomonas putida

Temperature Optimum [°C]

EC Number	Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
1.13.12.2	37	-	assay at	Pseudomonas putida

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
1.13.12.2	6.8	-	-	Pseudomonas putida

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Release 2023.1 (January 2023)