Literature summary extracted from

Chang, J.; Thia, C.; Lin, H.; Liu, H.; Ho, F.; Wu, J.; Shih, M.; Li, W.; Huang, C.
Integrating an algal beta-carotene hydroxylase gene into a designed carotenoid-biosynthesis pathway increases carotenoid production in yeast (2015), Biores. Technol., 184, 2-8 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.14.15.24	expressed in Kluyveromyces marxianus strain KY3	Chlamydomonas reinhardtii
1.14.15.24	expressed in Kluyveromyces marxianus strain KY3	Haematococcus lacustris
1.14.15.24	expressed in Kluyveromyces marxianus strain KY3	Chromochloris zofingiensis

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.15.24	beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2	Chlamydomonas reinhardtii	-	zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?
1.14.15.24	beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2	Haematococcus lacustris	-	zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?
1.14.15.24	beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2	Chromochloris zofingiensis	-	zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.15.24	Chlamydomonas reinhardtii	-	-	-
1.14.15.24	Chromochloris zofingiensis	-	-	-
1.14.15.24	Haematococcus lacustris	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.15.24	beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2	-	Chlamydomonas reinhardtii	zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?
1.14.15.24	beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2	-	Haematococcus lacustris	zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?
1.14.15.24	beta-carotene + reduced ferredoxin [iron-sulfur] cluster + H+ + O2	-	Chromochloris zofingiensis	zeaxanthin + oxidized ferredoxin [iron-sulfur] cluster + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.15.24	beta-carotene hydroxylase	-	Chlamydomonas reinhardtii
1.14.15.24	beta-carotene hydroxylase	-	Haematococcus lacustris
1.14.15.24	beta-carotene hydroxylase	-	Chromochloris zofingiensis
1.14.15.24	Chyb	-	Chlamydomonas reinhardtii
1.14.15.24	Chyb	-	Haematococcus lacustris
1.14.15.24	Chyb	-	Chromochloris zofingiensis

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Release 2023.1 (January 2023)