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Literature summary extracted from

  • Pandey, S.S.; Singh, S.; Babu, C.S.; Shanker, K.; Srivastava, N.K.; Kalra, A.
    Endophytes of opium poppy differentially modulate host plant productivity and genes for the biosynthetic pathway of benzylisoquinoline alkaloids (2016), Planta, 243, 1097-1114 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.11.31 oripavine + 2-oxoglutarate + O2 Papaver somniferum
-
 morphinone + formaldehyde + succinate + CO2
-
 ?
1.14.11.31 thebaine + 2-oxoglutarate + O2 Papaver somniferum
-
 neopinone + formaldehyde + succinate + CO2
-
 ?
1.14.11.32 codeine + 2-oxoglutarate + O2 Papaver somniferum
-
 morphine + formaldehyde + succinate + CO2
-
 ?
1.14.11.32 thebaine + 2-oxoglutarate + O2 Papaver somniferum
-
 oripavine + formaldehyde + succinate + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.31 Papaver somniferum
-
-
-
1.14.11.32 Papaver somniferum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.11.31 oripavine + 2-oxoglutarate + O2
-
 Papaver somniferum morphinone + formaldehyde + succinate + CO2
-
 ?
1.14.11.31 thebaine + 2-oxoglutarate + O2
-
 Papaver somniferum neopinone + formaldehyde + succinate + CO2
-
 ?
1.14.11.32 codeine + 2-oxoglutarate + O2
-
 Papaver somniferum morphine + formaldehyde + succinate + CO2
-
 ?
1.14.11.32 thebaine + 2-oxoglutarate + O2
-
 Papaver somniferum oripavine + formaldehyde + succinate + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.11.31 T6ODM
-
 Papaver somniferum
1.14.11.32 codeine O-demethylase
-
 Papaver somniferum
1.14.11.32 CODM
-
 Papaver somniferum

Expression

EC Number Organism Comment Expression
1.14.11.31 Papaver somniferum endophyte SM3B (Marmoricola sp.) can enhance enzyme expression by 2.5fold up
1.14.11.32 Papaver somniferum endophyte SM3B (Marmoricola sp.) can enhance enzyme expression by 2fold up