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Literature summary extracted from

  • Zhi, X.Y.; Yao, J.C.; Li, H.W.; Huang, Y.; Li, W.J.
    Genome-wide identification, domain architectures and phylogenetic analysis provide new insights into the early evolution of shikimate pathway in prokaryotes (2014), Mol. Phylogenet. Evol., 75, 154-164 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ Streptomyces griseus
-
 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ Stigmatella aurantiaca
-
 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ Streptomyces scabiei
-
 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ Frankia casuarinae
-
 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ Streptomyces griseus NBRC 13350
-
 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+ Streptomyces scabiei 87.22
-
 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+ Streptomyces griseus
-
 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+ Stigmatella aurantiaca
-
 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+ Streptomyces scabiei
-
 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+ Frankia casuarinae
-
 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+ Streptomyces griseus NBRC 13350
-
 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+ Streptomyces scabiei 87.22
-
 3-dehydroquinate + NH3 + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.24 Frankia casuarinae
-
-
-
1.4.1.24 Stigmatella aurantiaca
-
-
-
1.4.1.24 Streptomyces griseus
-
-
-
1.4.1.24 Streptomyces griseus NBRC 13350
-
-
-
1.4.1.24 Streptomyces scabiei
-
-
-
1.4.1.24 Streptomyces scabiei 87.22
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
 Streptomyces griseus 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
 Stigmatella aurantiaca 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
 Streptomyces scabiei 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
 Frankia casuarinae 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
 Streptomyces griseus NBRC 13350 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H2O + NAD+
-
 Streptomyces scabiei 87.22 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
 Streptomyces griseus 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
 Stigmatella aurantiaca 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
 Streptomyces scabiei 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
 Frankia casuarinae 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
 Streptomyces griseus NBRC 13350 3-dehydroquinate + NH3 + NADH + H+
-
 ?
1.4.1.24 3,7-dideoxy-D-threo-hepto-2,6-diulosonic acid + H2O + NAD+
-
 Streptomyces scabiei 87.22 3-dehydroquinate + NH3 + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.1.24 aroB2
-
 Streptomyces griseus
1.4.1.24 aroB2
-
 Stigmatella aurantiaca
1.4.1.24 aroB2
-
 Streptomyces scabiei
1.4.1.24 aroB2
-
 Frankia casuarinae
1.4.1.24 DHQ synthase
-
 Streptomyces griseus
1.4.1.24 DHQ synthase
-
 Stigmatella aurantiaca
1.4.1.24 DHQ synthase
-
 Streptomyces scabiei
1.4.1.24 DHQ synthase
-
 Frankia casuarinae
1.4.1.24 DHQS
-
 Streptomyces griseus
1.4.1.24 DHQS
-
 Stigmatella aurantiaca
1.4.1.24 DHQS
-
 Streptomyces scabiei
1.4.1.24 DHQS
-
 Frankia casuarinae
1.4.1.24 type II 3-dehydroquinate synthase
-
 Streptomyces griseus
1.4.1.24 type II 3-dehydroquinate synthase
-
 Stigmatella aurantiaca
1.4.1.24 type II 3-dehydroquinate synthase
-
 Streptomyces scabiei
1.4.1.24 type II 3-dehydroquinate synthase
-
 Frankia casuarinae

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.1.24 NAD+
-
 Streptomyces griseus
1.4.1.24 NAD+
-
 Stigmatella aurantiaca
1.4.1.24 NAD+
-
 Streptomyces scabiei
1.4.1.24 NAD+
-
 Frankia casuarinae