Literature summary extracted from

Gross, F.; Rudolf, E.E.; Thiele, B.; Durner, J.; Astier, J.
Copper amine oxidase 8 regulates arginine-dependent nitric oxide production in Arabidopsis thaliana (2017), J. Exp. Bot., 68, 2149-2162 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.4.3.21	expressed in Nicotiana benthamiana	Arabidopsis thaliana

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.4.3.21	aminoguanidine	irreversible inhibition	Arabidopsis thaliana

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.4.3.21	Arabidopsis thaliana	F4IAX0	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.4.3.21	Ni-NTA column chromatography	Arabidopsis thaliana

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.4.3.21	seedling	-	Arabidopsis thaliana	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.4.3.21	agmatine + H2O + O2	-	Arabidopsis thaliana	?	-	?
1.4.3.21	putrescine + H2O + O2	best substrate	Arabidopsis thaliana	?	-	?
1.4.3.21	spermidine + H2O + O2	-	Arabidopsis thaliana	?	-	?
1.4.3.21	spermine + H2O + O2	-	Arabidopsis thaliana	?	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.4.3.21	?	x * 95000, SDS-PAGE	Arabidopsis thaliana

Synonyms

EC Number	Synonyms	Comment	Organism
1.4.3.21	copper amine oxidase 8	-	Arabidopsis thaliana
1.4.3.21	CuAO8	-	Arabidopsis thaliana

General Information

EC Number	General Information	Comment	Organism
1.4.3.21	malfunction	total arginase activity is strongly increased in copper amine oxidase 8 knockout mutants after 2,6-dichloroisonicotinic acid and salt stress	Arabidopsis thaliana
1.4.3.21	physiological function	the enzyme participates in nitric oxide production by influencing arginine availability through the modulation of arginase activity and impacts primary root length	Arabidopsis thaliana

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Release 2023.1 (January 2023)