Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Gludovacz, E.; Maresch, D.; Bonta, M.; Szoelloesi, H.; Furtmueller, P.G.; Weik, R.; Altmann, F.; Limbeck, A.; Borth, N.; Jilma, B.; Boehm, T.
    Characterization of recombinant human diamine oxidase (rhDAO) produced in Chinese Hamster Ovary (CHO) cells (2016), J. Biotechnol., 227, 120-130 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.4.3.22 expressed in CHO-K1 cells Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.22 0.042
-
 putrescine at pH 8.0 and 30°C Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.4.3.22 Cu2+ one mol of dimeric enzyme is occupied with 1.99 mol copper Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.22 200000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.3.22 histamine + H2O + O2 Homo sapiens
-
 (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.22 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.22 benzylamine + H2O + O2 29% activity compared to putrescine Homo sapiens benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 histamine + H2O + O2
-
 Homo sapiens (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 histamine + H2O + O2 48% activity compared to putrescine Homo sapiens ?
-
 ?
1.4.3.22 putrescine + H2O + O2 100% activity Homo sapiens ?
-
 ?
1.4.3.22 spermidine + H2O + O2 71% activity compared to putrescine Homo sapiens ?
-
 ?
1.4.3.22 spermine + H2O + O2 42% activity compared to putrescine Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.22 homodimer 2 * 100000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
1.4.3.22 ABP1
-
 Homo sapiens
1.4.3.22 Amiloride-binding protein
-
 Homo sapiens
1.4.3.22 DAO
-
 Homo sapiens
1.4.3.22 histaminase
-
 Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.4.3.22 5.5
-
 putrescine at pH 8.0 and 30°C Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.22 L-topaquinone
-
 Homo sapiens