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Literature summary extracted from

  • Jeong, J.A.; Baek, E.Y.; Kim, S.W.; Choi, J.S.; Oh, J.I.
    Regulation of the ald gene encoding alanine dehydrogenase by AldR in Mycobacterium smegmatis (2013), J. Bacteriol., 195, 3610-3620 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.1 Mycolicibacterium smegmatis
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Expression

EC Number Organism Comment Expression
1.4.1.1 Mycolicibacterium smegmatis regulatory gene AldR serves as both activator and repressor for the regulation of ald gene expression, depending on the presence or absence of L-alanine. The purified AldR protein exists as a homodimer in the absence of L-alanine, while it adopts the quaternary structure of a homohexamer in the presence of L-alanine. The binding affinity of AldR for the ald control region is significantly increased by L-alanine additional information