Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Cano, M.; Volbeda, A.; Guedeney, G.; Aubert-Jousset, E.; Richaud, P.; Peltier, G.; Cournac, L.
    Improved oxygen tolerance of the Synechocystis sp. PCC 6803 bidirectional hydrogenase by site-directed mutagenesis of putative residues of the gas diffusion channel (2014), Int. J. Hydrogen Energy, 39, 16872-16884 .
No PubMed abstract available

Protein Variants

EC Number Protein Variants Comment Organism
1.12.1.2 I64M the mutation alters gas diffusion kinetics and improves O2 tolerance Synechocystis sp.
1.12.1.2 I64M/L107M the mutant shows strongly reduced activity compared to the wild type enzyme Synechocystis sp.
1.12.1.2 I64M/L107M/L112M the mutant shows strongly reduced activity compared to the wild type enzyme Synechocystis sp.
1.12.1.2 I64M/L112M the mutant shows strongly reduced activity compared to the wild type enzyme Synechocystis sp.
1.12.1.2 L107F the mutant shows reduced activity compared to the wild type enzyme Synechocystis sp.
1.12.1.2 L107M/L112M the mutant shows reduced activity compared to the wild type enzyme Synechocystis sp.
1.12.1.2 L112F the mutant shows strongly reduced activity compared to the wild type enzyme Synechocystis sp.
1.12.1.2 L112M the mutant shows slightly reduced activity compared to the wild type enzyme Synechocystis sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.12.1.2 H2 + NAD+ Synechocystis sp.
-
H+ + NADH
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.12.1.2 Synechocystis sp.
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.12.1.2 H2 + NAD+
-
Synechocystis sp. H+ + NADH
-
?

Subunits

EC Number Subunits Comment Organism
1.12.1.2 ? x * 50000, SDS-PAGE Synechocystis sp.

Synonyms

EC Number Synonyms Comment Organism
1.12.1.2 HoxH subunit Synechocystis sp.
1.12.1.2 HoxY subunit Synechocystis sp.
1.12.1.2 [NiFe] hydrogenase
-
Synechocystis sp.