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Literature summary extracted from

  • Giuffre, A.; Borisov, V.B.; Arese, M.; Sarti, P.; Forte, E.
    Cytochrome bd oxidase and bacterial tolerance to oxidative and nitrosative stress (2014), Biochim. Biophys. Acta, 1837, 1178-1187 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.3 nitric oxide reversible inhibition Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.3 membrane
-
Escherichia coli 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.1.1.3 ubiquinol + O2 + H+[side 1] Escherichia coli
-
ubiquinone + H2O + H+[side 2]
-
?
7.1.1.7 ubiquinol + O2 + H+[side 1] Escherichia coli
-
ubiquinone + H2O + H+[side 2]
-
?

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.3 Escherichia coli
-
-
-
7.1.1.7 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.3 ubiquinol + O2 + H+[side 1]
-
Escherichia coli ubiquinone + H2O + H+[side 2]
-
?
7.1.1.7 ubiquinol + O2 + H+[side 1]
-
Escherichia coli ubiquinone + H2O + H+[side 2]
-
?

Subunits

EC Number Subunits Comment Organism
7.1.1.3 ? x * 57000 + x * 43000 + x * 4000, SDS-PAGE Escherichia coli
7.1.1.7 heterotrimer 1 * 57000 + 1 * 43000 + 1 * 4000, SDS-PAGE Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
7.1.1.3 CydA subunit Escherichia coli
7.1.1.3 CydB subunit Escherichia coli
7.1.1.3 CydX subunit Escherichia coli
7.1.1.3 cytochrome bd
-
Escherichia coli
7.1.1.3 cytochrome bd oxidase
-
Escherichia coli
7.1.1.7 CydA
-
Escherichia coli
7.1.1.7 CydB
-
Escherichia coli
7.1.1.7 CydX
-
Escherichia coli
7.1.1.7 cytochrome bd oxidase
-
Escherichia coli
7.1.1.7 cytochrome bd-I
-
Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.3 heme the enzyme contains the low spin hexacoordinate heme b558 and the high spin pentacoordinate hemes b595 and d Escherichia coli
7.1.1.7 heme
-
Escherichia coli

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
7.1.1.3 0.0001
-
pH and temperature not specified in the publication Escherichia coli nitric oxide

General Information

EC Number General Information Comment Organism
7.1.1.7 physiological function the expression of cytochrome bd enhances bacterial tolerance to nitrosative stress Escherichia coli