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Literature summary extracted from

  • Hiser, C.; Buhrow, L.; Liu, J.; Kuhn, L.; Ferguson-Miller, S.
    A conserved amphipathic ligand binding region influences K-path-dependent activity of cytochrome C oxidase (2013), Biochemistry, 52, 1385-1396 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.1.1.9 (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate
-
Cereibacter sphaeroides
7.1.1.9 arachidonic acid
-
Cereibacter sphaeroides
7.1.1.9 phytanic acid
-
Cereibacter sphaeroides

Protein Variants

EC Number Protein Variants Comment Organism
7.1.1.9 E10A the mutant shows 50% of wild type activity Cereibacter sphaeroides

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.9 C12E8
-
Cereibacter sphaeroides
7.1.1.9 chenodeoxycholate
-
Cereibacter sphaeroides
7.1.1.9 CHOBIMALT
-
Cereibacter sphaeroides
7.1.1.9 cholate
-
Cereibacter sphaeroides
7.1.1.9 dodecyl beta-D-maltopyranoside
-
Cereibacter sphaeroides
7.1.1.9 lithocholate
-
Cereibacter sphaeroides
7.1.1.9 lysophophatidylcholine
-
Cereibacter sphaeroides
7.1.1.9 additional information ursodeoxycholateand glycochenodeoxycholate have no observable effect on enzyme activity Cereibacter sphaeroides
7.1.1.9 Triton X-100
-
Cereibacter sphaeroides

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.9 membrane
-
Cereibacter sphaeroides 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.1.1.9 ferrocytochrome c + O2 + H+ Cereibacter sphaeroides
-
ferricytochrome c + H2O
-
?
7.1.1.9 ferrocytochrome c + O2 + H+ Cereibacter sphaeroides 37-2
-
ferricytochrome c + H2O
-
?

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.9 Cereibacter sphaeroides P33517
-
-
7.1.1.9 Cereibacter sphaeroides 37-2 P33517
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.1.1.9 metal affinity column chromatography Cereibacter sphaeroides

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.9 ferrocytochrome c + O2 + H+
-
Cereibacter sphaeroides ferricytochrome c + H2O
-
?
7.1.1.9 ferrocytochrome c + O2 + H+
-
Cereibacter sphaeroides 37-2 ferricytochrome c + H2O
-
?

Synonyms

EC Number Synonyms Comment Organism
7.1.1.9 CCO
-
Cereibacter sphaeroides
7.1.1.9 cytochrome c oxidase
-
Cereibacter sphaeroides

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.9 heme
-
Cereibacter sphaeroides