Literature summary extracted from

Park, J.S.; Yeom, M.H.; Park, W.S.; Joo, K.M.; Rho, H.S.; Kim, D.H.; Chang, I.S.
Enzymatic hydrolysis of green tea seed extract and its activity on 5alpha-reductase inhibition (2006), Biosci. Biotechnol. Biochem., 70, 387-94.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.3.99.5	kaempferol	-	Homo sapiens
1.3.99.5	additional information	green tea seed extract hydrolysate shows a good inhibition effect on HEK 293 cell lines on both type 1 and type 2 5alpha-reductase	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.3.99.5	testosterone + reduced acceptor	Homo sapiens	-	5alpha-dihydrotestosterone + acceptor	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.99.5	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.3.99.5	HEK-293 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.99.5	testosterone + reduced acceptor	-	Homo sapiens	5alpha-dihydrotestosterone + acceptor	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.3.99.5	5alpha reductase	-	Homo sapiens
1.3.99.5	5alphaR1	-	Homo sapiens
1.3.99.5	5alphaR2	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)