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Literature summary extracted from

  • Prasad, U.V.; Swarupa, V.; Yeswanth, S.; Kumar, P.S.; Kumar, E.S.; Reddy, K.M.; Kumar, Y.N.; Rani, V.J.; Chaudhary, A.; Sarma, P.V.
    Structural and functional analysis of Staphylococcus aureus NADP-dependent IDH and its comparison with bacterial and human NADP-dependent IDH (2014), Bioinformation, 10, 81-86.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.42 DNA and amino acid sequence analysis Staphylococcus aureus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.42 crystal structures analysis using PDB IDs 1T09 and 1T0L Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.42 cytosol
-
 Homo sapiens 5829
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.42 Homo sapiens O75874
-
-
1.1.1.42 Staphylococcus aureus D7RIE8
-
-
1.1.1.42 Staphylococcus aureus ATCC 12600 D7RIE8
-
-

Subunits

EC Number Subunits Comment Organism
1.1.1.42 More three-dimensional structure modelling, structure comparison with the enzyme from Staphylococcus aureus, overview Homo sapiens
1.1.1.42 More three-dimensional structure modelling, structure comparison with the human enzyme, PDB IDs 1T09 and 1T0L, overview Staphylococcus aureus

Synonyms

EC Number Synonyms Comment Organism
1.1.1.42 NADP-dependent IDH
-
 Homo sapiens
1.1.1.42 NADP-dependent IDH
-
 Staphylococcus aureus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.42 NADP+
-
 Homo sapiens
1.1.1.42 NADP+
-
 Staphylococcus aureus

General Information

EC Number General Information Comment Organism
1.1.1.42 additional information three-dimensional structure modelling, isocitrate substrate docking, overview Homo sapiens
1.1.1.42 additional information three-dimensional structure modelling, isocitrate substrate docking, overview Staphylococcus aureus
1.1.1.42 physiological function the enzyme dictates the flow of carbon as part of the Krebs cycle thereby controlling the virulence and biofilm formation Homo sapiens
1.1.1.42 physiological function the enzyme dictates the flow of carbon as part of the Krebs cycle thereby controlling the virulence and biofilm formation Staphylococcus aureus