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Literature summary extracted from

  • Paidimuddala, B.; Rathod, A.; Gummadi, S.
    Inhibition of Debaryomyces nepalensis xylose reductase by lignocellulose derived by-products (2017), Biochem. Eng. J., 121, 73-82.
No PubMed abstract available

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.431 in complex with vanillin, phenol, gallic acid, furfural Debaryomyces nepalensis

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.431 5-hydroxymethylfurfural mixed inhibition type Debaryomyces nepalensis
1.1.1.431 acetate mixed inhibition type Debaryomyces nepalensis
1.1.1.431 furfural mixed inhibition type Debaryomyces nepalensis
1.1.1.431 gallic acid mixed inhibition type Debaryomyces nepalensis
1.1.1.431 phenol competitive inhibition Debaryomyces nepalensis
1.1.1.431 Vanillin mixed inhibition type Debaryomyces nepalensis

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.431 Debaryomyces nepalensis A0A0M4HL56
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.431 163
-
 pH 7.0, 45°C Debaryomyces nepalensis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.431 D-xylose + NADPH + H+
-
 Debaryomyces nepalensis xylitol + NADP+
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.431 0.1
-
 Vanillin pH 7.0, 45°C Debaryomyces nepalensis
1.1.1.431 11
-
 phenol pH 7.0, 45°C Debaryomyces nepalensis
1.1.1.431 32
-
 gallic acid pH 7.0, 45°C Debaryomyces nepalensis
1.1.1.431 45
-
 5-hydroxymethylfurfural pH 7.0, 45°C Debaryomyces nepalensis
1.1.1.431 54
-
 furfural pH 7.0, 45°C Debaryomyces nepalensis
1.1.1.431 100
-
 acetate pH 7.0, 45°C Debaryomyces nepalensis