EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.101 | 2-Methyl-1,2-di(3-pyridyl)-1-propanone | i.e. methyrapone | Thalictrum bulgaricum | |
1.14.14.101 | 5-hydroxy-1,4-naphthoquinone | i.e. juglone | Thalictrum bulgaricum | |
1.14.14.101 | CO | inhibition in the dark, effect is partly reversible upon illumination | Thalictrum bulgaricum | |
1.14.14.101 | cytochrome c | - |
Thalictrum bulgaricum | |
1.14.14.101 | ketoconazole | - |
Thalictrum bulgaricum |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.14.101 | microsome | associated with | Thalictrum bulgaricum | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.101 | dihydrochelirubine + [reduced NADPH-hemoprotein reductase] + O2 | Thalictrum bulgaricum | involved the penultimate step in the biosynthesis of macarpine, the most highly oxidized benzophenanthridine alkaloid found in nature | 12-hydroxydihydrochelirubine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
2.1.1.120 | S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine | Thalictrum bulgaricum | involved in biosynthesis of macarpine, the most highly oxidized benzophenanthridine alkaloid, not significantly affected by elicitation | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.101 | Thalictrum bulgaricum | - |
- |
- |
2.1.1.120 | Thalictrum bulgaricum | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.1.120 | - |
Thalictrum bulgaricum |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.14.101 | cell culture | yeast-elicited cells | Thalictrum bulgaricum | - |
2.1.1.120 | cell culture | - |
Thalictrum bulgaricum | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.101 | dihydrochelirubine + [reduced NADPH-hemoprotein reductase] + O2 | - |
Thalictrum bulgaricum | 12-hydroxydihydrochelirubine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
1.14.14.101 | dihydrochelirubine + [reduced NADPH-hemoprotein reductase] + O2 | involved the penultimate step in the biosynthesis of macarpine, the most highly oxidized benzophenanthridine alkaloid found in nature | Thalictrum bulgaricum | 12-hydroxydihydrochelirubine + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
2.1.1.120 | S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine | - |
Thalictrum bulgaricum | S-adenosyl-L-homocysteine + dihydromacarpine | - |
? | |
2.1.1.120 | S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine | involved in biosynthesis of macarpine, the most highly oxidized benzophenanthridine alkaloid, not significantly affected by elicitation | Thalictrum bulgaricum | ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.14.101 | 30 | - |
- |
Thalictrum bulgaricum |
2.1.1.120 | 30 | - |
- |
Thalictrum bulgaricum |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.14.101 | 8.5 | - |
- |
Thalictrum bulgaricum |
2.1.1.120 | 7.5 | - |
- |
Thalictrum bulgaricum |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.101 | cytochrome P450 | dependent on | Thalictrum bulgaricum |