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Literature summary extracted from

  • Li, G.; Liu, L.; Li, P.; Chen, L.; Song, H.; Zhang, Y.
    Gene expression profiling of selenophosphate synthetase 2 knockdown in Drosophila melanogaster (2016), Metallomics, 8, 354-365.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.9.3 gene SPS2, gene expression profiles of the knockdown of SPS2 in larval and adult stages, quantitative real-time PCR enzyme exxpression analysis in wild-type and mutant strains, detailed overview Drosophila melanogaster

Protein Variants

EC Number Protein Variants Comment Organism
2.7.9.3 additional information the SPS2 mutant strain, which contains a P element transposon insertion in the 5th exon of the SPS2 gene and causes a hypomorphic allele, is back-crossed with w1118 control flies for six generations to equilibrate the genetic background Drosophila melanogaster

Organism

EC Number Organism UniProt Comment Textmining
2.7.9.3 Drosophila melanogaster
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.9.3 adult
-
 Drosophila melanogaster
-
2.7.9.3 larva
-
 Drosophila melanogaster
-

Synonyms

EC Number Synonyms Comment Organism
2.7.9.3 selenophosphate synthetase
-
 Drosophila melanogaster
2.7.9.3 Sps2
-
 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
2.7.9.3 malfunction in the enzyme knockout mutant, the function of SPS2 proteins is significantly inhibited, it is possible that the expression levels of selenoproteins in fruit flies might be reduced Drosophila melanogaster
2.7.9.3 metabolism considering that Se utilization and homeostasis may play a role in diabetogenesis and some other metabolic disorder, regucalcin can become a potential link between the Se metabolism and those metabolic disorders/diseases Drosophila melanogaster
2.7.9.3 physiological function enzyme SPS2 may play an important role in regulating basic metabolic pathways as well as redox homeostasis, probably via some of the key regulators. The product of SPS2, selenophosphate, activity is required during the translation of selenoprotein genes Drosophila melanogaster