Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Zhou, M.L.; Qi, L.P.; Pang, J.F.; Zhang, Q.; Lei, Z.; Tang, Y.X.; Zhu, X.M.; Shao, J.R.; Wu, Y.M.
    Nicotianamine synthase gene family as central components in heavy metal and phytohormone response in maize (2013), Funct. Integr. Genomics, 13, 229-239.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.43 gene ZmNAS1, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS10, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS2, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS3, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis, recombinant expression of C-terminally GFP-tagged ZmNAS3 in the cytoplasm of transgenic Arabidopsis leaf protoplasts Zea mays
2.5.1.43 gene ZmNAS4, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS5, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS6, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS7, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS8, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays
2.5.1.43 gene ZmNAS9, promoter identification, genotyping and isozyme sequence comparisons, phylogenetic analysis, quantitative RT-PCR expression analysis Zea mays

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.43 chloroplast the sequence contains a chloroplast transit peptide Zea mays 9507
-
2.5.1.43 mitochondrion the sequence contains a mitochondrial targeting peptide Zea mays 5739
-
2.5.1.43 secretory vesicle
-
Zea mays 99503
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.43 35500
-
-
Zea mays
2.5.1.43 35570
-
-
Zea mays
2.5.1.43 35620
-
-
Zea mays
2.5.1.43 35680
-
-
Zea mays
2.5.1.43 38190
-
-
Zea mays
2.5.1.43 38800
-
-
Zea mays
2.5.1.43 65840
-
-
Zea mays

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.43 3 S-adenosyl-L-methionine Zea mays
-
3 S-methyl-5'-thioadenosine + nicotianamine
-
?
2.5.1.43 3 S-adenosyl-L-methionine Zea mays B73
-
3 S-methyl-5'-thioadenosine + nicotianamine
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.43 Zea mays A0A1D6GLB9 gene ZmNAS5
-
2.5.1.43 Zea mays A0A1D6IP14 gene ZmNAS6
-
2.5.1.43 Zea mays A0A1D6K0A7 gene ZmNAS4
-
2.5.1.43 Zea mays A0A1D6K0A8 gene ZmNAS2
-
2.5.1.43 Zea mays B4FAC0 gene ZmNAS7
-
2.5.1.43 Zea mays K7VEJ7 gene ZmNAS10
-
2.5.1.43 Zea mays K7VIY6 gene ZmNAS8
-
2.5.1.43 Zea mays K7WE51 gene ZmNAS9
-
2.5.1.43 Zea mays Q8LT22 gene ZmNAS3
-
2.5.1.43 Zea mays Q8S9C5 gene ZmNAS1
-
2.5.1.43 Zea mays B73 A0A1D6GLB9 gene ZmNAS5
-
2.5.1.43 Zea mays B73 A0A1D6IP14 gene ZmNAS6
-
2.5.1.43 Zea mays B73 A0A1D6K0A7 gene ZmNAS4
-
2.5.1.43 Zea mays B73 A0A1D6K0A8 gene ZmNAS2
-
2.5.1.43 Zea mays B73 B4FAC0 gene ZmNAS7
-
2.5.1.43 Zea mays B73 K7VEJ7 gene ZmNAS10
-
2.5.1.43 Zea mays B73 K7VIY6 gene ZmNAS8
-
2.5.1.43 Zea mays B73 K7WE51 gene ZmNAS9
-
2.5.1.43 Zea mays B73 Q8LT22 gene ZmNAS3
-
2.5.1.43 Zea mays B73 Q8S9C5 gene ZmNAS1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.43 leaf very low expression Zea mays
-
2.5.1.43 additional information the ZmNAS genes show differential, organ-specific expression patterns in the maize developmental steps, RT-PCR expression analysis, overview Zea mays
-
2.5.1.43 root exclusively Zea mays
-
2.5.1.43 root very low expression Zea mays
-
2.5.1.43 seedling
-
Zea mays
-
2.5.1.43 stem very low expression Zea mays
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.43 3 S-adenosyl-L-methionine
-
Zea mays 3 S-methyl-5'-thioadenosine + nicotianamine
-
?
2.5.1.43 3 S-adenosyl-L-methionine the enzyme catalyzes trimerization of S-adenosyl-L-methionine and ring formation to synthesize nicotinamine Zea mays 3 S-methyl-5'-thioadenosine + nicotianamine
-
?
2.5.1.43 3 S-adenosyl-L-methionine
-
Zea mays B73 3 S-methyl-5'-thioadenosine + nicotianamine
-
?
2.5.1.43 3 S-adenosyl-L-methionine the enzyme catalyzes trimerization of S-adenosyl-L-methionine and ring formation to synthesize nicotinamine Zea mays B73 3 S-methyl-5'-thioadenosine + nicotianamine
-
?

Subunits

EC Number Subunits Comment Organism
2.5.1.43 ? x * 35500, sequence calculation Zea mays
2.5.1.43 ? x * 35570, sequence calculation Zea mays
2.5.1.43 ? x * 35620, sequence calculation Zea mays
2.5.1.43 ? x * 35680, sequence calculation Zea mays
2.5.1.43 ? x * 38190, sequence calculation Zea mays
2.5.1.43 ? x * 38800, sequence calculation Zea mays
2.5.1.43 ? x * 45320, sequence calculation Zea mays
2.5.1.43 ? x * 65840, sequence calculation Zea mays
2.5.1.43 ? x * 65940, sequence calculation Zea mays

Synonyms

EC Number Synonyms Comment Organism
2.5.1.43 NAS
-
Zea mays
2.5.1.43 ZmNAS1
-
Zea mays
2.5.1.43 ZmNAS10
-
Zea mays
2.5.1.43 ZmNAS2
-
Zea mays
2.5.1.43 ZmNAS3
-
Zea mays
2.5.1.43 ZmNAS4
-
Zea mays
2.5.1.43 ZmNAS5
-
Zea mays
2.5.1.43 ZmNAS6
-
Zea mays
2.5.1.43 ZmNAS7
-
Zea mays
2.5.1.43 ZmNAS8
-
Zea mays
2.5.1.43 ZmNAS9
-
Zea mays

Cofactor

EC Number Cofactor Comment Organism Structure
2.5.1.43 S-adenosyl-L-methionine
-
Zea mays

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.5.1.43 Zea mays sequence calculation
-
5.49
2.5.1.43 Zea mays sequence calculation
-
5.68
2.5.1.43 Zea mays sequence calculation
-
5.89
2.5.1.43 Zea mays sequence calculation
-
5.99
2.5.1.43 Zea mays sequence calculation
-
6.08
2.5.1.43 Zea mays sequence calculation
-
6.09
2.5.1.43 Zea mays sequence calculation
-
6.15
2.5.1.43 Zea mays sequence calculation
-
6.22

Expression

EC Number Organism Comment Expression
2.5.1.43 Zea mays ZmNAS1 gene is suppressed by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd down
2.5.1.43 Zea mays ZmNAS10 is downregulated by Ni down
2.5.1.43 Zea mays ZmNAS2 gene is suppressed by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd down
2.5.1.43 Zea mays ZmNAS3 gene is uppressed by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd down
2.5.1.43 Zea mays ZmNAS5 is downregulated by Cd, Cu, Ni, and Mn down
2.5.1.43 Zea mays ZmNAS6 is downregulated by Ni down
2.5.1.43 Zea mays ZmNAS7 is downregulated by Cu and Ni down
2.5.1.43 Zea mays ZmNAS8 gene is responsive to heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd down
2.5.1.43 Zea mays ZmNAS9 is downregulated by Ni, Mn, Fe, and Zn down
2.5.1.43 Zea mays all ZmNAS genes are responsive to heavy metal ions (Ni, Fe, Cu, Mn, Zn, and Cd). ZmNAS gene expression of maize seedlings is regulated by jasmonic acid, abscisic acid, and salicylic acid additional information
2.5.1.43 Zea mays ZmNAS gene expression of maize seedlings is regulated by jasmonic acid, abscisic acid, and salicylic acid additional information
2.5.1.43 Zea mays ZmNAS4 gene is induced by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd up
2.5.1.43 Zea mays ZmNAS7 gene is induced by Fe up

General Information

EC Number General Information Comment Organism
2.5.1.43 additional information homology modeling using Oryzsa sative isozymes as template Zea mays
2.5.1.43 physiological function nicotianamine is an important divalent metal chelator and the main precursor of phytosiderophores. nicotianamine is synthesized from S-adenosylmethionine in a process catalyzed by nicotianamine synthase, NAS. Expression of ZmNAS genes is tissue-specific and developmentally regulated Zea mays