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Literature summary extracted from

  • Jadav, R.S.; Kumar, D.; Buwa, N.; Ganguli, S.; Thampatty, S.R.; Balasubramanian, N.; Bhandari, R.
    Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice (2016), Cell. Signal., 28, 1124-1136.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.4.21 55000
-
 x * 55000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.21 ATP + 1D-myo-inositol hexakisphosphate Mus musculus
-
 ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.21 Mus musculus Q6PD10
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.21 MEF cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.21 ATP + 1D-myo-inositol hexakisphosphate
-
 Mus musculus ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.4.21 ? x * 55000, SDS-PAGE Mus musculus

Synonyms

EC Number Synonyms Comment Organism
2.7.4.21 inositol hexakisphosphate kinase 1
-
 Mus musculus
2.7.4.21 IP6K1
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.7.4.21 malfunction enzyme deletion reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma Mus musculus
2.7.4.21 physiological function the enzyme is involved in early cytoskeleton remodeling events during cancer progression and essential for 4-nitroquinoline-1-oxide-induced invasive carcinoma Mus musculus