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Literature summary extracted from
- The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate (2016), Arch. Biochem. Biophys., 604, 159-166.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.14.14.35 | expression in Escherichia coli | Pseudomonas fluorescens |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.14.14.35 | 40000 | - |
x * 40000, SDS-PAGE | Pseudomonas fluorescens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.35 | dimethyl sulfone + FMNH2 + O2 | Pseudomonas fluorescens | - |
methanesulfinate + formaldehyde + FMN + H2O | - |
? |  |
| 1.14.14.35 | dimethyl sulfone + FMNH2 + O2 | Pseudomonas fluorescens Pf0-1 | - |
methanesulfinate + formaldehyde + FMN + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.35 | Pseudomonas fluorescens | Q3KC85 | - |
- |
| 1.14.14.35 | Pseudomonas fluorescens Pf0-1 | Q3KC85 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.35 | dimethyl sulfone + FMNH2 + O2 | - |
Pseudomonas fluorescens | methanesulfinate + formaldehyde + FMN + H2O | - |
? | |
| 1.14.14.35 | dimethyl sulfone + FMNH2 + O2 | - |
Pseudomonas fluorescens Pf0-1 | methanesulfinate + formaldehyde + FMN + H2O | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.14.14.35 | ? | x * 40000, SDS-PAGE | Pseudomonas fluorescens |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.14.35 | Pfl01_2879 | - |
Pseudomonas fluorescens |
| 1.14.14.35 | sfnG | - |
Pseudomonas fluorescens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.35 | FMNH2 | - |
Pseudomonas fluorescens | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.14.14.35 | physiological function | enzyme SfnG functions as a flavoprotein monooxygenase and converts DMSO2 to methanesulfinate in the presence of FMN, NADH, and FMN reductase MsuE | Pseudomonas fluorescens |
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Release 2023.1 (January 2023)
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