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Literature summary extracted from

  • Vijayaraghavan, S.; Karami, A.; Aeinehband, S.; Behbahani, H.; Grandien, A.; Nilsson, B.; Ekdahl, K.N.; Lindblom, R.P.; Piehl, F.; Darreh-Shori, T.
    Regulated extracellular choline acetyltransferase activity - the plausible missing link of the distant action of acetylcholine in the cholinergic anti-inflammatory pathway (2013), PLoS ONE, 8, e65936.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.6 soluble
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.6 65000
-
 x * 65000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.6 acetyl-CoA + choline Homo sapiens
-
 CoA + O-acetylcholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.6 Homo sapiens P28329
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.6 astrocyte
-
 Homo sapiens
-
2.3.1.6 blood plasma
-
 Homo sapiens
-
2.3.1.6 cerebrospinal fluid
-
 Homo sapiens
-
2.3.1.6 embryonic stem cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.6 acetyl-CoA + choline
-
 Homo sapiens CoA + O-acetylcholine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.6 ? x * 65000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.3.1.6 ChAT
-
 Homo sapiens
2.3.1.6 choline-acetyltransferase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.6 38
-
-
 Homo sapiens

Expression

EC Number Organism Comment Expression
2.3.1.6 Homo sapiens cerebral spinal fluid enzyme is upregulated in autoimmune neuroinflammation up

General Information

EC Number General Information Comment Organism
2.3.1.6 physiological function soluble cerebrospinal fluid enzyme levels show strong correlation with soluble complement factor levels, supporting a role in inflammatory regulation Homo sapiens