EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.3.2.B8 | S68A | the mutant shows wild type activity | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.2.B8 | 21400 | - |
1 * 21400, calculated from amino acid sequence | Homo sapiens |
2.3.2.B8 | 22400 | - |
1 * 22400, SEC-MALS analysis | Homo sapiens |
2.3.2.25 | 22400 | - |
1 * 22400, calculated from amino acid sequence | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.B8 | S-ubiquitinyl-[ubiquitin-carrier protein E2]-L-cysteine + [HECT-E3-ubiquitin-carrier protein]-L-cysteine | Homo sapiens | - |
[ubiquitin-carrier protein E2]-L-cysteine + S-ubiquitinyl-[HECT-E3-ubiquitin-carrier protein]-L-cysteine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.2.B8 | Homo sapiens | - |
- |
- |
2.3.2.25 | Homo sapiens | P51965 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.2.B8 | additional information | the full-length UBE2E proteins primarily promote protein monoubiquitylation, whereas the core UBC domain of each can efficiently build polyubiquitin chains | Homo sapiens | ? | - |
? | |
2.3.2.B8 | S-ubiquitinyl-[ubiquitin-carrier protein E2]-L-cysteine + [HECT-E3-ubiquitin-carrier protein cIAP2]-L-cysteine | - |
Homo sapiens | [ubiquitin-carrier protein E2]-L-cysteine + S-ubiquitinyl-[HECT-E3-ubiquitin-carrier protein cIAP2]-L-cysteine | - |
? | |
2.3.2.B8 | S-ubiquitinyl-[ubiquitin-carrier protein E2]-L-cysteine + [HECT-E3-ubiquitin-carrier protein]-L-cysteine | - |
Homo sapiens | [ubiquitin-carrier protein E2]-L-cysteine + S-ubiquitinyl-[HECT-E3-ubiquitin-carrier protein]-L-cysteine | - |
? | |
2.3.2.25 | S-ubiquitinyl-[N-terminal E2 ubiquitin-conjugating E2 enzyme]-L-cysteine + [CARP2 protein]-N-terminal-amino acid | - |
Homo sapiens | [N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine + N-ubiquitinyl-[ CARP2 protein]-N-terminal amino acid | - |
? | |
2.3.2.25 | S-ubiquitinyl-[N-terminal E2 ubiquitin-conjugating E2 enzyme]-L-cysteine + [cIAP2 protein]-N-terminal-amino acid | - |
Homo sapiens | [N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine + N-ubiquitinyl-[ cIAP2 protein]-N-terminal amino acid | - |
? | |
2.3.2.25 | S-ubiquitinyl-[N-terminal E2 ubiquitin-conjugating E2 enzyme]-L-cysteine + [MDM2 protein]-N-terminal-amino acid | - |
Homo sapiens | [N-terminal E2 ubiquitin-conjugating enzyme]-L-cysteine + N-ubiquitinyl-[ MDM2 protein]-N-terminal amino acid | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.2.B8 | monomer | 1 * 21400, calculated from amino acid sequence | Homo sapiens |
2.3.2.B8 | monomer | 1 * 22400, SEC-MALS analysis | Homo sapiens |
2.3.2.25 | monomer | 1 * 22400, calculated from amino acid sequence | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.2.B8 | UbcH6 | - |
Homo sapiens |
2.3.2.B8 | UBE2E1 | - |
Homo sapiens |
2.3.2.25 | UbcH6 | - |
Homo sapiens |
2.3.2.25 | UBE2E1 | - |
Homo sapiens |
2.3.2.25 | ubiquitin-conjugating enzyme (E2) | - |
Homo sapiens |