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Literature summary extracted from

  • Hao, N.; Mu, J.; Hu, N.; Xu, S.; Yan, M.; Li, Y.; Guo, K.; Xu, L.
    Improvement of L-citrulline production in Corynebacterium glutamicum by ornithine acetyltransferase (2015), J. Ind. Microbiol. Biotechnol., 42, 307-313.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.35 gene argJ, recombinant overexpression in Corynebacterium glutamicum strain ATCC 13032 Corynebacterium glutamicum

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.35 additional information L-citrulline overproduction in Corynebacterium glutamicum engineered strain correlates with expression levels of ArgJ, which plays a vital role in the L-citrulline biosynthesis Corynebacterium glutamicum

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.35 L-citrulline
-
 Corynebacterium glutamicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.35 N2-acetyl-L-ornithine + L-glutamate Corynebacterium glutamicum
-
 L-ornithine + N-acetyl-L-glutamate
-
 ?
2.3.1.35 N2-acetyl-L-ornithine + L-glutamate Corynebacterium glutamicum ATCC 13032
-
 L-ornithine + N-acetyl-L-glutamate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.35 Corynebacterium glutamicum Q59280 gene argJ
-
2.3.1.35 Corynebacterium glutamicum ATCC 13032 Q59280 gene argJ
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.35 N2-acetyl-L-ornithine + L-glutamate
-
 Corynebacterium glutamicum L-ornithine + N-acetyl-L-glutamate
-
 ?
2.3.1.35 N2-acetyl-L-ornithine + L-glutamate
-
 Corynebacterium glutamicum ATCC 13032 L-ornithine + N-acetyl-L-glutamate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.35 argJ
-
 Corynebacterium glutamicum
2.3.1.35 OATase
-
 Corynebacterium glutamicum
2.3.1.35 ornithine acetyltransferase
-
 Corynebacterium glutamicum

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.35 37
-
 assay at Corynebacterium glutamicum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.35 7.5
-
 assay at Corynebacterium glutamicum

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.3.1.35 30
-
 pH 7.5, 37°C Corynebacterium glutamicum L-citrulline

General Information

EC Number General Information Comment Organism
2.3.1.35 metabolism ArgJ plays a vital role in the L-citrulline biosynthesis. The enzyme exerts feedback inhibition on N-acetylglutamate synthase, pathway overview Corynebacterium glutamicum