Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Boroughs, L.K.; Antonyak, M.A.; Cerione, R.A.
    A novel mechanism by which tissue transglutaminase activates signaling events that promote cell survival (2014), J. Biol. Chem., 289, 10115-10125.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.2.13 expressed in HEK-293T cells Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.13 [protein]-L-glutamine + alkylamine Mus musculus
-
 [protein]-N5-alkyl-L-glutamine + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 NIH-3T3 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 [protein]-L-glutamine + alkylamine
-
 Mus musculus [protein]-N5-alkyl-L-glutamine + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.2.13 tissue transglutaminase
-
 Mus musculus
2.3.2.13 tTG
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.3.2.13 metabolism the enzyme activates PI3-kinase Mus musculus
2.3.2.13 physiological function the enzyme has an intrinsic capability to promote cell survival and contributes to oncogenesis Mus musculus