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Literature summary extracted from

  • Dempsey, D.R.; Jeffries, K.A.; Anderson, R.L.; Carpenter, A.M.; Rodriquez Opsina, S.; Merkler, D.J.
    Identification of an arylalkylamine N-acyltransferase from Drosophila melanogaster that catalyzes the formation of long-chain N-acylserotonins (2014), FEBS Lett., 588, 594-599.
    View publication on PubMedView publication on EuropePMC

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.87 0.0018
-
butanoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.0019
-
Arachidonoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.0036
-
oleoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.006
-
stearoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.0061
-
acetyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.0099
-
palmitoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.87 Drosophila melanogaster Q9VMG0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.87 acetyl-CoA + serotonin
-
Drosophila melanogaster CoA + N-acetylserotonin
-
?
2.3.1.87 acetyl-CoA + tyramine
-
Drosophila melanogaster CoA + N-acetyltyramine
-
?
2.3.1.87 arachidonoyl-CoA + octopamine
-
Drosophila melanogaster CoA + N-arachidonoyloctopamine
-
?
2.3.1.87 butanoyl-CoA + dopamine
-
Drosophila melanogaster CoA + N-butanoyldopamine
-
?
2.3.1.87 oleoyl-CoA + octopamine
-
Drosophila melanogaster CoA + N-oleoyloctopamine
-
?
2.3.1.87 palmitoyl-CoA + octopamine
-
Drosophila melanogaster CoA + N-palmitoyloctopamine
-
?
2.3.1.87 stearoyl-CoA + octopamine
-
Drosophila melanogaster CoA + N-stearoyloctopamine
-
?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.87 AATNATL2
-
Drosophila melanogaster

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.3.1.87 0.043
-
Arachidonoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.059
-
stearoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.075
-
oleoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.16
-
palmitoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 0.53
-
butanoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 1.3
-
acetyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster

General Information

EC Number General Information Comment Organism
2.3.1.87 physiological function isoform AANATL2 has a role in the biosynthetic formation of long-chain N-acylserotonins and N-acydopamines Drosophila melanogaster

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
2.3.1.87 9.8
-
stearoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 16
-
palmitoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 21
-
oleoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 23
-
Arachidonoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 220
-
acetyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster
2.3.1.87 290
-
butanoyl-CoA pH 8.0, temperature not specified in the publication Drosophila melanogaster