Literature summary extracted from

Grove, T.; Livada, J.; Schwalm, E.; Green, M.; Booker, S.; Silakov, A.
A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr (2013), Nat. Chem. Biol., 9, 422-427.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.1.192	S-adenosyl-L-methionine + adenine2503 in 23S rRNA	Staphylococcus aureus	the enzyme methylates C8 in adenine2503 in 23S rRNA	S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2-methyladenine2503 in 23S rRNA	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.192	Staphylococcus aureus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.192	S-adenosyl-L-methionine + adenine2503 in 23S rRNA	the enzyme methylates C8 in adenine2503 in 23S rRNA	Staphylococcus aureus	S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2-methyladenine2503 in 23S rRNA	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.1.192	Cfr	-	Staphylococcus aureus

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Release 2023.1 (January 2023)