Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Laranjeira, S.; Amorim-Silva, V.; Esteban, A.; Arro, M.; Ferrer, A.; Tavares, R.M.; Botella, M.A.; Rosado, A.; Azevedo, H.
    Arabidopsis squalene epoxidase 3 (SQE3) complements SQE1 and is important for embryo development and bulk squalene epoxidase activity (2015), Mol. Plant, 8, 1090-1102.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.17 terbinafine
-
 Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.14.17 endoplasmic reticulum
-
 Arabidopsis thaliana 5783
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.17 squalene + [reduced NADPH-hemoprotein reductase] + O2 Arabidopsis thaliana
-
 (3S)-2,3-epoxy-2,3-dihydrosqualene + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.17 Arabidopsis thaliana
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.17 leaf
-
 Arabidopsis thaliana
-
1.14.14.17 root
-
 Arabidopsis thaliana
-
1.14.14.17 shoot
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.17 squalene + [reduced NADPH-hemoprotein reductase] + O2
-
 Arabidopsis thaliana (3S)-2,3-epoxy-2,3-dihydrosqualene + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.17 SQE3 isoform Arabidopsis thaliana
1.14.14.17 squalene epoxidase 3 isoform Arabidopsis thaliana

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.14.14.17 0.0009
-
 pH and temperature not specified in the publication Arabidopsis thaliana terbinafine

General Information

EC Number General Information Comment Organism
1.14.14.17 metabolism the isoform SQE3 is able to complement isoform SQE1 function Arabidopsis thaliana
1.14.14.17 physiological function the enzyme is important for embryo development and bulk squalene epoxidase activity Arabidopsis thaliana