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Literature summary extracted from

  • Roy, V.; Smith, J.A.; Wang, J.; Stewart, J.E.; Bentley, W.E.; Sintim, H.O.
    Synthetic analogs tailor native AI-2 signaling across bacterial species (2010), J. Am. Chem. Soc., 132, 11141-11150.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.189 Mg2+ required Salmonella enterica subsp. enterica serovar Typhimurium
2.7.1.189 Mg2+ required Escherichia coli
2.7.1.189 Mg2+ required Vibrio harveyi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Vibrio harveyi
-
ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose Vibrio harveyi BB170
-
ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione Vibrio harveyi BB170
-
ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione Vibrio harveyi BB170
-
ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxydecane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxydecane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyheptane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyheptane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyhexane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyhexane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxynonane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxynonane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyoctane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyoctane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyundecane-3,4-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyundecane-3,4-dione Vibrio harveyi
-
ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
?
2.7.1.189 ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
?
2.7.1.189 ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione Vibrio harveyi
-
ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
?
2.7.1.189 ATP + 4,5-dihydroxypentane-2,3-dione Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
?
2.7.1.189 ATP + 4,5-dihydroxypentane-2,3-dione Vibrio harveyi
-
ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
?
2.7.1.189 ATP + autoinducer-2 Salmonella enterica subsp. enterica serovar Typhimurium i.e. AI-2 ADP + phosphorylated autoinducer-2
-
?
2.7.1.189 ATP + autoinducer-2 Escherichia coli i.e. AI-2 ADP + phosphorylated autoinducer-2
-
?
2.7.1.189 ATP + autoinducer-2 Vibrio harveyi i.e. AI-2 ADP + phosphorylated autoinducer-2
-
?
2.7.1.189 additional information Salmonella enterica subsp. enterica serovar Typhimurium no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
?
2.7.1.189 additional information Vibrio harveyi no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
?
2.7.1.189 additional information Salmonella enterica subsp. enterica serovar Typhimurium the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
?
2.7.1.189 additional information Escherichia coli the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
?
2.7.1.189 additional information Vibrio harveyi the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
?
2.7.1.189 additional information Salmonella enterica subsp. enterica serovar Typhimurium MET715 no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
?
2.7.1.189 additional information Salmonella enterica subsp. enterica serovar Typhimurium MET715 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
?
2.7.1.189 additional information Escherichia coli W3110 / ATCC 27325 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
?
2.7.1.189 additional information Salmonella enterica subsp. enterica serovar Typhimurium MET708 no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
?
2.7.1.189 additional information Salmonella enterica subsp. enterica serovar Typhimurium MET708 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
?
2.7.1.189 additional information Vibrio harveyi BB170 no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview ?
-
?
2.7.1.189 additional information Vibrio harveyi BB170 the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.189 Escherichia coli
-
gene lsrK
-
2.7.1.189 Escherichia coli W3110 / ATCC 27325
-
gene lsrK
-
2.7.1.189 Salmonella enterica subsp. enterica serovar Typhimurium
-
gene lsrK
-
2.7.1.189 Salmonella enterica subsp. enterica serovar Typhimurium MET708
-
gene lsrK
-
2.7.1.189 Salmonella enterica subsp. enterica serovar Typhimurium MET715
-
gene lsrK
-
2.7.1.189 Vibrio harveyi
-
gene lsrK
-
2.7.1.189 Vibrio harveyi BB170
-
gene lsrK
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
Escherichia coli ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
Vibrio harveyi ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
Salmonella enterica subsp. enterica serovar Typhimurium MET715 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
Escherichia coli W3110 / ATCC 27325 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
Salmonella enterica subsp. enterica serovar Typhimurium MET708 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dideoxy-2-ethylhexo-3,4-diulose
-
Vibrio harveyi BB170 ADP + 1,2-dideoxy-2-ethyl-6-O-phosphonohexo-3,4-diulose
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium MET715 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
Escherichia coli W3110 / ATCC 27325 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium MET708 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-5-methylhexane-3,4-dione
-
Vibrio harveyi BB170 ADP + 2-hydroxy-5-methyl-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium MET715 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
Escherichia coli W3110 / ATCC 27325 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium MET708 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6,6-dimethylheptane-3,4-dione
-
Vibrio harveyi BB170 ADP + 2-hydroxy-6,6-dimethyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxy-6-methylheptane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-6-methyl-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxydecane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxydecane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxydecane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-3,4-dioxodecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyheptane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyheptane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyheptane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-3,4-dioxoheptyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyhexane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyhexane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyhexane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-3,4-dioxohexyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxynonane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxynonane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxynonane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-3,4-dioxononyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyoctane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyoctane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyoctane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-3,4-dioxooctyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyundecane-3,4-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyundecane-3,4-dione
-
Escherichia coli ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
?
2.7.1.189 ATP + 1,2-dihydroxyundecane-3,4-dione
-
Vibrio harveyi ADP + 2-hydroxy-3,4-dioxoundecyl phosphate
-
?
2.7.1.189 ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
?
2.7.1.189 ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione
-
Escherichia coli ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
?
2.7.1.189 ATP + 1-cyclopropyl-3,4-dihydroxybutane-1,2-dione
-
Vibrio harveyi ADP + 4-cyclopropyl-2-hydroxy-3,4-dioxobutyl phosphate
-
?
2.7.1.189 ATP + 4,5-dihydroxypentane-2,3-dione
-
Salmonella enterica subsp. enterica serovar Typhimurium ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
?
2.7.1.189 ATP + 4,5-dihydroxypentane-2,3-dione
-
Escherichia coli ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
?
2.7.1.189 ATP + 4,5-dihydroxypentane-2,3-dione
-
Vibrio harveyi ADP + 2-hydroxy-3,4-dioxopentyl phosphate
-
?
2.7.1.189 ATP + autoinducer-2 i.e. AI-2 Salmonella enterica subsp. enterica serovar Typhimurium ADP + phosphorylated autoinducer-2
-
?
2.7.1.189 ATP + autoinducer-2 i.e. AI-2 Escherichia coli ADP + phosphorylated autoinducer-2
-
?
2.7.1.189 ATP + autoinducer-2 i.e. AI-2 Vibrio harveyi ADP + phosphorylated autoinducer-2
-
?
2.7.1.189 additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Salmonella enterica subsp. enterica serovar Typhimurium ?
-
?
2.7.1.189 additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Escherichia coli ?
-
?
2.7.1.189 additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Vibrio harveyi ?
-
?
2.7.1.189 additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
?
2.7.1.189 additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Escherichia coli ?
-
?
2.7.1.189 additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Vibrio harveyi ?
-
?
2.7.1.189 additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Salmonella enterica subsp. enterica serovar Typhimurium MET715 ?
-
?
2.7.1.189 additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Salmonella enterica subsp. enterica serovar Typhimurium MET715 ?
-
?
2.7.1.189 additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Escherichia coli W3110 / ATCC 27325 ?
-
?
2.7.1.189 additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Escherichia coli W3110 / ATCC 27325 ?
-
?
2.7.1.189 additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Salmonella enterica subsp. enterica serovar Typhimurium MET708 ?
-
?
2.7.1.189 additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Salmonella enterica subsp. enterica serovar Typhimurium MET708 ?
-
?
2.7.1.189 additional information no phosphorylation of deoxy-AI-2-analogues by LsrK. Synthesis of substrate analogues and activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview Vibrio harveyi BB170 ?
-
?
2.7.1.189 additional information the enzyme also phosphorylates and activates C-1 alkyl analogues of autoinducer-2, AI-2 Vibrio harveyi BB170 ?
-
?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.189 lsrK
-
Salmonella enterica subsp. enterica serovar Typhimurium
2.7.1.189 lsrK
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Escherichia coli
2.7.1.189 lsrK
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Vibrio harveyi

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.189 7.4
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assay at Salmonella enterica subsp. enterica serovar Typhimurium
2.7.1.189 7.4
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assay at Escherichia coli
2.7.1.189 7.4
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assay at Vibrio harveyi

General Information

EC Number General Information Comment Organism
2.7.1.189 metabolism the enzyme is involved in quorum sensing, overview Salmonella enterica subsp. enterica serovar Typhimurium
2.7.1.189 metabolism the enzyme is involved in quorum sensing, overview Escherichia coli
2.7.1.189 metabolism the enzyme is involved in quorum sensing, overview Vibrio harveyi
2.7.1.189 physiological function autoinducer-2, AI-2, is activated by the bacterial kinase LsrK and modulate AI-2 specific gene transcription through the transcriptional regulator LsrR. Activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview. In vivo, the critical step that makes AI-2 functional in derepressing the lsr operon is phosphorylation by the kinase LsrK. Active autinducer 2 and its analogues quench the quorum sensing response in multiple bacterial species simultaneously, overview Salmonella enterica subsp. enterica serovar Typhimurium
2.7.1.189 physiological function autoinducer-2, AI-2, is activated by the bacterial kinase LsrK and modulate AI-2 specific gene transcription through the transcriptional regulator LsrR. Activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview. In vivo, the critical step that makes AI-2 functional in derepressing the lsr operon is phosphorylation by the kinase LsrK. Active autinducer 2 and its analogues quench the quorum sensing response in multiple bacterial species simultaneously, overview Escherichia coli
2.7.1.189 physiological function autoinducer-2, AI-2, is activated by the bacterial kinase LsrK and modulate AI-2 specific gene transcription through the transcriptional regulator LsrR. Activities of phosphorylated autoinducer 2 analogues in quorum sensing reduction, overview. In vivo, the critical step that makes AI-2 functional in derepressing the lsr operon is phosphorylation by the kinase LsrK. Active autinducer 2 and its analogues quench the quorum sensing response in multiple bacterial species simultaneously, overview Vibrio harveyi