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Literature summary extracted from

  • Quan, G.; Ladd, T.; Duan, J.; Wen, F.; Doucet, D.; Cusson, M.; Krell, P.J.
    Characterization of a spruce budworm chitin deacetylase gene: stage- and tissue-specific expression, and inhibition using RNA interference (2013), Insect Biochem. Mol. Biol., 43, 683-691.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.1.41 gene CfCDA2a, DNA and amino acid sequence determination and analysis, genetic structure, sequence comparisons, quantitative real-time RT-PCR expression analysis Choristoneura fumiferana
3.5.1.41 gene CfCDA2b, DNA and amino acid sequence determination and analysis, genetic structure, sequence comparisons, quantitative real-time RT-PCR expression analysis Choristoneura fumiferana

Protein Variants

EC Number Protein Variants Comment Organism
3.5.1.41 additional information RNAi-induced depletion of CfCDA2 transcripts, CfCDA2 transcript levels are strongly suppressed in 5thand 6th-instar larvae injected with CfCDA2-specific dsRNA, compared to controls, CfCDA2 transcript levels are 20% and 50% those of controls in injected 5th- and 6th-instar larvae, respectively Choristoneura fumiferana

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.5.1.41 61000
-
 x * 61000, about, isozyme B, sequence calculation Choristoneura fumiferana
3.5.1.41 62000
-
 x * 62000, about, isozyme A, sequence calculation Choristoneura fumiferana

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.41 Choristoneura fumiferana S5YT69 isozyme b; gene CDA2, splice variant isozyme B
-
3.5.1.41 Choristoneura fumiferana S5Z6S1 isozyme a; gene CDA2, splice variant isozyme A
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.41 epidermis epidermis of molting larvae and day 0 pupae Choristoneura fumiferana
-
3.5.1.41 larva
-
 Choristoneura fumiferana
-
3.5.1.41 additional information the signal is absent or faint in the midgut and larval fat body, tissue- and stage-specific expression of the isozyme, overview Choristoneura fumiferana
-

Subunits

EC Number Subunits Comment Organism
3.5.1.41 ? x * 61000, about, isozyme B, sequence calculation Choristoneura fumiferana
3.5.1.41 ? x * 62000, about, isozyme A, sequence calculation Choristoneura fumiferana

Synonyms

EC Number Synonyms Comment Organism
3.5.1.41 CDA
-
 Choristoneura fumiferana

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.5.1.41 Choristoneura fumiferana isozyme A, sequence calculation
-
 4.6
3.5.1.41 Choristoneura fumiferana isozyme B, sequence calculation
-
 4.6

General Information

EC Number General Information Comment Organism
3.5.1.41 malfunction enzyme silencing results in abnormal molting phenotypes Choristoneura fumiferana
3.5.1.41 additional information the isoforms differ only in the alternatively spliced region, representing 43 and 37 amino acid residues in isoforms A and B, respectively Choristoneura fumiferana
3.5.1.41 physiological function the strong expression of CfCDA2 in the epidermis of molting individuals points to an important role of this gene in the molting process of Choristoneura fumiferana Choristoneura fumiferana