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Literature summary extracted from

  • Shanks, R.; Stella, N.; Hunt, K.; Brothers, K.; Zhang, L.; Thibodeau, P.
    Identification of SlpB, a cytotoxic protease from Serratia marcescens (2015), Infect. Immun., 83, 2907-2916.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.40 expressed in Escherichia coli Serratia marcescens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.40 alkaline protease inhibitor
-
 Serratia marcescens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.40 Ca2+ dependent on Serratia marcescens

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.40 Serratia marcescens
-
-
-
3.4.24.40 Serratia marcescens PIC3611
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.40
-
 Serratia marcescens

Synonyms

EC Number Synonyms Comment Organism
3.4.24.40 SlpB
-
 Serratia marcescens

Expression

EC Number Organism Comment Expression
3.4.24.40 Serratia marcescens secretion of SlpB requires type I secretion protein LipD up

General Information

EC Number General Information Comment Organism
3.4.24.40 malfunction strain K904 with deletion of both prtS and slpB genes is defective in secreted protease activity and cytotoxicity to human cell lines Serratia marcescens
3.4.24.40 physiological function the enzyme exhibits cytotoxicity to airway and ocular cell lines in vitro Serratia marcescens