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Literature summary extracted from

  • Garton, S.; Michaelson, L.V.; Beaudoin, F.; Beale, M.H.; Napier, J.A.
    The dihydroceramide desaturase is not essential for cell viability in Schizosaccharomyces pombe (2003), FEBS Lett., 538, 192-196.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.17 expressed in Saccharomyces cerevisiae strain w303-1a Schizosaccharomyces pombe

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.19.17 dihydroceramide + ferrocytochrome b5 + O2 + H+ Schizosaccharomyces pombe
-
 (4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.17 Schizosaccharomyces pombe O59715
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.17 dihydroceramide + ferrocytochrome b5 + O2 + H+
-
 Schizosaccharomyces pombe (4E)-sphing-4-enine ceramide + ferricytochrome b5 + H2O
-
 ?
1.14.19.17 additional information the enzyme does not recognise fatty acids and trihydroxylated sphingoid long-chain bases as substrate Schizosaccharomyces pombe ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.17 dehydroceramide desaturase
-
 Schizosaccharomyces pombe
1.14.19.17 dihydroceramide DELTA4-desaturase
-
 Schizosaccharomyces pombe
1.14.19.17 SPBC3B8.07c
-
 Schizosaccharomyces pombe

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.17 cytochrome b5
-
 Schizosaccharomyces pombe

General Information

EC Number General Information Comment Organism
1.14.19.17 physiological function the enzyme has no effect on cell viability Schizosaccharomyces pombe