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Literature summary extracted from
- On the catalytic mechanism of dimeric dUTPases (2013), Biochem. J., 456, 81-88.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.6.1.23 | expression in Escherichia coli | Trypanosoma brucei |
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 3.6.1.23 | transition state analogue complexes in presence of dUMP, AlF3 and MgF3-. In the dimeric enzyme, the nucleophilic attack occurs on the beta-phosphate group | Trypanosoma brucei |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.6.1.23 | Trypanosoma brucei | Q57ZH3 | - |
- |
| 3.6.1.23 | Trypanosoma brucei 927/4 | Q57ZH3 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.6.1.23 | dUTP + H2O | - |
Trypanosoma brucei | dUMP + diphosphate | - |
? |  |
| 3.6.1.23 | dUTP + H2O | - |
Trypanosoma brucei 927/4 | dUMP + diphosphate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.6.1.23 | Tb927.7.5160 | - |
Trypanosoma brucei |
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Release 2023.1 (January 2023)
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