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Literature summary extracted from

  • Ishiyama, D.; Vujaklija, D.; Davies, J.
    Novel pathway of salicylate degradation by Streptomyces sp. strain WA46 (2004), Appl. Environ. Microbiol., 70, 1297-1306.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.209 expressed in Streptomyces lividans TK64 and Escherichia coli DH10B cells Streptomyces sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.13.209 56600
-
 x * 56600, calculated from amino acid sequence Streptomyces sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.209 2-hydroxybenzoyl-CoA + NADH + H+ + O2 Streptomyces sp.
-
 gentisyl-CoA + NAD+ + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.209 Streptomyces sp. Q7X281
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.209 2-hydroxybenzoyl-CoA + NADH + H+ + O2
-
 Streptomyces sp. gentisyl-CoA + NAD+ + H2O
-
 ?
1.14.13.209 additional information direct conversion of salicylate to gentisate is not observed Streptomyces sp. ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.13.209 ? x * 56600, calculated from amino acid sequence Streptomyces sp.

Synonyms

EC Number Synonyms Comment Organism
1.14.13.209 salicylyl-CoA 5-hydroxylase
-
 Streptomyces sp.
1.14.13.209 sdgC
-
 Streptomyces sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.209 NADH required, neither NADPH nor FAD can replace NADH Streptomyces sp.