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Literature summary extracted from

  • Carroll, R.; Rivera, F.; Cavaco, C.; Johnson, G.; Martin, D.; Shaw, L.
    The lone S41 family C-terminal processing protease in Staphylococcus aureus is localized to the cell wall and contributes to virulence (2014), Microbiology, 160, 1737-1748.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.102 cell wall
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Staphylococcus aureus 5618
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Organism

EC Number Organism UniProt Comment Textmining
3.4.21.102 Staphylococcus aureus
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-
-

Synonyms

EC Number Synonyms Comment Organism
3.4.21.102 C-terminal processing protease
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Staphylococcus aureus
3.4.21.102 CtpA
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Staphylococcus aureus

Expression

EC Number Organism Comment Expression
3.4.21.102 Staphylococcus aureus expression of the ctpA gene encoding C-terminal processing protease is maximal upon exposure to conditions encountered during infection up

General Information

EC Number General Information Comment Organism
3.4.21.102 physiological function disruption of the ctpA gene leads to decreased heat tolerance and increased sensitivity when exposed to components of the host immune system. The ctpA” mutant strain is attenuated for virulence in a murine model of infection Staphylococcus aureus