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Literature summary extracted from

  • Kaewsuwan, S.; Cahoon, E.B.; Perroud, P.F.; Wiwat, C.; Panvisavas, N.; Quatrano, R.S.; Cove, D.J.; Bunyapraphatsara, N.
    Identification and functional characterization of the moss Physcomitrella patens DELTA5-desaturase gene involved in arachidonic and eicosapentaenoic acid biosynthesis (2006), J. Biol. Chem., 281, 21988-21997.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.30 expression of the enzyme in Saccharomyces cerevisiae results in the production of the DELTA5-containing fatty acid arachidonic acid in cells that are provided di-homo-gamma-linolenic acid Physcomitrium patens

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.30 Physcomitrium patens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.30 an (8Z,11Z,14Z)-icosa-8,11,14-trienoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ (8Z,11Z,14Z)-icosa-8,11,14-trienoate i.e. di-homo-gamma-linolenate. Expression of the enzyme in Saccharomyces cerevisiae results in the production of the DELTA5-containing fatty acid arachidonic acid in cells that are provided di-homo-gamma-linolenic acid Physcomitrium patens a (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoyl-[glycerolipid] + ferricytochrome b5 + 2 H2O (5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-tetraenoate i.e. arachidonate ?
1.14.19.30 an (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
-
Physcomitrium patens a (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-[glycerolipid] + ferricytochrome b5 + 2 H2O
-
?
1.14.19.30 additional information no products are detected with the C18 fatty acid linoleic and gamma-linolenic acids or with the C22 fatty acid adrenic and docosapentaenoic acids Physcomitrium patens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.30 DELTA5-desaturase
-
Physcomitrium patens
1.14.19.30 PPDES5
-
Physcomitrium patens