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Literature summary extracted from

  • Ito, Y.; Fukami, T.; Yokoi, T.; Nakajima, M.
    An Orphan esterase ABHD10 modulates probenecid acyl glucuronidation in human liver (2014), Drug Metab. Dispos., 42, 2109-2116.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.93 bis-p-nitrophenylphosphate
-
 Homo sapiens
3.1.1.93 Disulfiram
-
 Homo sapiens
3.1.1.93 DTNB
-
 Homo sapiens
3.1.1.93 phenylmethylsulfonyl fluoride
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.93 AgNO3 inhibition Homo sapiens
3.1.1.93 CuCl2 inhibition Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.93 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.93 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.93 7400
-
 pH 7.4, 37°C Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.1.93 ABHD10
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.93 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.93 7.4
-
 assay at Homo sapiens

General Information

EC Number General Information Comment Organism
3.1.1.93 metabolism probenecid acyl glucuronide (PRAG) deglucuronidation catalyzed by ABHD10 suppressively regulates probenecid acyl glucuronide (PRAG) formation via multiple UGT enzymes in human liver Homo sapiens