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Literature summary extracted from

  • Pokotylo, I.; Pejchar, P.; Potocky, M.; Kocourkova, D.; Krckova, Z.; Ruelland, E.; Kravets, V.; Martinec, J.
    The plant non-specific phospholipase C gene family. Novel competitors in lipid signalling (2013), Prog. Lipid Res., 52, 62-79.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.4.3 expression of the N-terminal domain in Escherichia coli Clostridium perfringens
3.1.4.3 phylogenetic analysis Nicotiana tabacum
3.1.4.3 phylogenetic analysis Glycine max
3.1.4.3 phylogenetic analysis Sorghum bicolor
3.1.4.3 phylogenetic analysis Oryza sativa
3.1.4.3 phylogenetic analysis Petunia x hybrida
3.1.4.3 phylogenetic analysis Physcomitrium patens
3.1.4.3 phylogenetic analysis Vitis vinifera
3.1.4.3 phylogenetic analysis Populus trichocarpa
3.1.4.3 phylogenetic analysis Picea sitchensis
3.1.4.3 phylogenetic analysis Selaginella moellendorffii
3.1.4.3 phylogenetic analysis Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
3.1.4.3 up the enzyme is induced by 24-epibrassinolide signalling, auxin, cytokinin, phosphate deficiency, abscisic acid, and salt stress. NPC4 does demonstrate a positive response to Botrytis cinerea, Golovinomyces orontii, Pseudomonas syringae and Phytophthora infestans treatment Arabidopsis thaliana

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.3 additional information no inhibition by tricyclodecan-9-ylxanthogenate, i.e. D609 Nicotiana tabacum
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609; i.e. D609; i.e. D609; i.e. D609; i.e. D609; i.e. D609 Arabidopsis thaliana
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Bacillus cereus
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Clostridium perfringens
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Glycine max
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Oryza sativa
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Petunia x hybrida
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Physcomitrium patens
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Picea sitchensis
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Populus trichocarpa
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Pseudomonas fluorescens
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Selaginella moellendorffii
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Sorghum bicolor
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Ureaplasma urealyticum
3.1.4.3 tricyclodecan-9-ylxanthogenate i.e. D609 Vitis vinifera

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.3 chloroplast
-
 Arabidopsis thaliana 9507
-
3.1.4.3 cytosol
-
 Arabidopsis thaliana 5829
-
3.1.4.3 endoplasmic reticulum membrane
-
 Arabidopsis thaliana 5789
-
3.1.4.3 extracellular the enzyme is secreted Clostridium perfringens
-
-
3.1.4.3 membrane bound Ureaplasma urealyticum 16020
-
3.1.4.3 membrane of stamens and pistils Petunia x hybrida 16020
-
3.1.4.3 mitochondrion
-
 Arabidopsis thaliana 5739
-
3.1.4.3 plasma membrane
-
 Nicotiana tabacum 5886
-
3.1.4.3 plasma membrane
-
 Arabidopsis thaliana 5886
-
3.1.4.3 tonoplast
-
 Arabidopsis thaliana
-
-
3.1.4.3 vacuolar membrane
-
 Arabidopsis thaliana 5774
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.3 Nal activates enzyme activity Ureaplasma urealyticum
3.1.4.3 Zn2+ bound at the N-terminal domain Clostridium perfringens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.3 phosphatidylcholine + H2O Glycine max
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Pseudomonas fluorescens
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Bacillus cereus
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Sorghum bicolor
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Oryza sativa
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Petunia x hybrida
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Clostridium perfringens
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Ureaplasma urealyticum
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Physcomitrium patens
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Vitis vinifera
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Populus trichocarpa
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Picea sitchensis
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Selaginella moellendorffii
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O Arabidopsis thaliana
-
 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylethanolamine + H2O Arabidopsis thaliana
-
 1,2-sn-diacylglycerol + phosphoethanolamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.3 Arabidopsis thaliana O81020 NPC2; gene NPC2
-
3.1.4.3 Arabidopsis thaliana Q8H965 NPC6; gene NPC6
-
3.1.4.3 Arabidopsis thaliana Q8L7Y9 NPC1; gene NPC1
-
3.1.4.3 Arabidopsis thaliana Q9S816 NPC5; gene NPC5
-
3.1.4.3 Arabidopsis thaliana Q9SRQ6 NPC3; gene NPC3
-
3.1.4.3 Arabidopsis thaliana Q9SRQ7 NPC4; gene NPC4
-
3.1.4.3 Bacillus cereus
-
-
-
3.1.4.3 Clostridium perfringens
-
-
-
3.1.4.3 Glycine max
-
 six genes NPC1-6
-
3.1.4.3 Nicotiana tabacum
-
-
-
3.1.4.3 Oryza sativa
-
 six genes NPC1-6
-
3.1.4.3 Petunia x hybrida
-
 six genes NPC1-6
-
3.1.4.3 Physcomitrium patens
-
 single NPC1-like gene
-
3.1.4.3 Picea sitchensis
-
 NPC1-, NPC2- and NPC6-like gene, no NPC3-5
-
3.1.4.3 Populus trichocarpa
-
 six genes NPC1-6
-
3.1.4.3 Pseudomonas fluorescens
-
-
-
3.1.4.3 Selaginella moellendorffii
-
 single NPC1-like gene
-
3.1.4.3 Sorghum bicolor
-
 six genes NPC1-6
-
3.1.4.3 Ureaplasma urealyticum
-
-
-
3.1.4.3 Vitis vinifera
-
 six genes NPC1-6
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.3 native enzyme Ureaplasma urealyticum

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Nicotiana tabacum
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Glycine max
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Sorghum bicolor
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Oryza sativa
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Petunia x hybrida
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Physcomitrium patens
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Vitis vinifera
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Populus trichocarpa
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Picea sitchensis
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Selaginella moellendorffii
a
3.1.4.3 a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine mode of action of the plant enzyme family of non-specific phospholipases C, overview Arabidopsis thaliana
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.3 cell suspension culture
-
 Nicotiana tabacum
-
3.1.4.3 cotyledon
-
 Arabidopsis thaliana
-
3.1.4.3 inflorescence
-
 Arabidopsis thaliana
-
3.1.4.3 leaf
-
 Arabidopsis thaliana
-
3.1.4.3 leaf old Arabidopsis thaliana
-
3.1.4.3 additional information tissue distribution, overview Arabidopsis thaliana
-
3.1.4.3 pistil
-
 Petunia x hybrida
-
3.1.4.3 pollen germinating Arabidopsis thaliana
-
3.1.4.3 root
-
 Arabidopsis thaliana
-
3.1.4.3 seedling higher in seedling hypocotyls and lower in seedling roots Arabidopsis thaliana
-
3.1.4.3 silique
-
 Arabidopsis thaliana
-
3.1.4.3 stamen
-
 Petunia x hybrida
-
3.1.4.3 TBY-2 cell
-
 Nicotiana tabacum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.3 phosphatidic acid + H2O
-
 Arabidopsis thaliana 1,2-sn-diacylglycerol + phosphate
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Glycine max 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Pseudomonas fluorescens 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Bacillus cereus 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Sorghum bicolor 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Oryza sativa 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Petunia x hybrida 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Clostridium perfringens 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Ureaplasma urealyticum 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Physcomitrium patens 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Vitis vinifera 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Populus trichocarpa 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Picea sitchensis 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Selaginella moellendorffii 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylcholine + H2O
-
 Arabidopsis thaliana 1,2-sn-diacylglycerol + phosphocholine
-
 ?
3.1.4.3 phosphatidylethanolamine + H2O
-
 Arabidopsis thaliana 1,2-sn-diacylglycerol + phosphoethanolamine
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Nicotiana tabacum
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Glycine max
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Sorghum bicolor
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Oryza sativa
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Petunia x hybrida
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Physcomitrium patens
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Vitis vinifera
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Populus trichocarpa
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Picea sitchensis
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Selaginella moellendorffii
3.1.4.3 More the enzyme contains a central phosphoesterase domain, a DUF756 domain, a conserved region and a conserved Asp-Arg pair, and some isozymes contain a signal peptide, domain structure, overview Arabidopsis thaliana

Synonyms

EC Number Synonyms Comment Organism
3.1.4.3 alpha-toxin
-
 Clostridium perfringens
3.1.4.3 non-specific phospholipase C
-
 Nicotiana tabacum
3.1.4.3 non-specific phospholipase C
-
 Glycine max
3.1.4.3 non-specific phospholipase C
-
 Sorghum bicolor
3.1.4.3 non-specific phospholipase C
-
 Oryza sativa
3.1.4.3 non-specific phospholipase C
-
 Petunia x hybrida
3.1.4.3 non-specific phospholipase C
-
 Physcomitrium patens
3.1.4.3 non-specific phospholipase C
-
 Vitis vinifera
3.1.4.3 non-specific phospholipase C
-
 Populus trichocarpa
3.1.4.3 non-specific phospholipase C
-
 Picea sitchensis
3.1.4.3 non-specific phospholipase C
-
 Selaginella moellendorffii
3.1.4.3 non-specific phospholipase C
-
 Arabidopsis thaliana
3.1.4.3 NPC
-
 Nicotiana tabacum
3.1.4.3 NPC
-
 Glycine max
3.1.4.3 NPC
-
 Sorghum bicolor
3.1.4.3 NPC
-
 Oryza sativa
3.1.4.3 NPC
-
 Petunia x hybrida
3.1.4.3 NPC
-
 Physcomitrium patens
3.1.4.3 NPC
-
 Vitis vinifera
3.1.4.3 NPC
-
 Populus trichocarpa
3.1.4.3 NPC
-
 Picea sitchensis
3.1.4.3 NPC
-
 Selaginella moellendorffii
3.1.4.3 NPC
-
 Arabidopsis thaliana
3.1.4.3 NPC1
-
 Glycine max
3.1.4.3 NPC1
-
 Sorghum bicolor
3.1.4.3 NPC1
-
 Oryza sativa
3.1.4.3 NPC1
-
 Petunia x hybrida
3.1.4.3 NPC1
-
 Physcomitrium patens
3.1.4.3 NPC1
-
 Vitis vinifera
3.1.4.3 NPC1
-
 Populus trichocarpa
3.1.4.3 NPC1
-
 Picea sitchensis
3.1.4.3 NPC1
-
 Selaginella moellendorffii
3.1.4.3 NPC1
-
 Arabidopsis thaliana
3.1.4.3 NPC2
-
 Glycine max
3.1.4.3 NPC2
-
 Sorghum bicolor
3.1.4.3 NPC2
-
 Oryza sativa
3.1.4.3 NPC2
-
 Petunia x hybrida
3.1.4.3 NPC2
-
 Vitis vinifera
3.1.4.3 NPC2
-
 Populus trichocarpa
3.1.4.3 NPC2
-
 Picea sitchensis
3.1.4.3 NPC2
-
 Arabidopsis thaliana
3.1.4.3 NPC3
-
 Glycine max
3.1.4.3 NPC3
-
 Sorghum bicolor
3.1.4.3 NPC3
-
 Oryza sativa
3.1.4.3 NPC3
-
 Petunia x hybrida
3.1.4.3 NPC3
-
 Vitis vinifera
3.1.4.3 NPC3
-
 Populus trichocarpa
3.1.4.3 NPC3
-
 Arabidopsis thaliana
3.1.4.3 NPC4
-
 Glycine max
3.1.4.3 NPC4
-
 Sorghum bicolor
3.1.4.3 NPC4
-
 Oryza sativa
3.1.4.3 NPC4
-
 Petunia x hybrida
3.1.4.3 NPC4
-
 Vitis vinifera
3.1.4.3 NPC4
-
 Populus trichocarpa
3.1.4.3 NPC4
-
 Arabidopsis thaliana
3.1.4.3 NPC5
-
 Glycine max
3.1.4.3 NPC5
-
 Sorghum bicolor
3.1.4.3 NPC5
-
 Oryza sativa
3.1.4.3 NPC5
-
 Petunia x hybrida
3.1.4.3 NPC5
-
 Vitis vinifera
3.1.4.3 NPC5
-
 Populus trichocarpa
3.1.4.3 NPC5
-
 Arabidopsis thaliana
3.1.4.3 NPC6
-
 Glycine max
3.1.4.3 NPC6
-
 Sorghum bicolor
3.1.4.3 NPC6
-
 Oryza sativa
3.1.4.3 NPC6
-
 Petunia x hybrida
3.1.4.3 NPC6
-
 Vitis vinifera
3.1.4.3 NPC6
-
 Populus trichocarpa
3.1.4.3 NPC6
-
 Picea sitchensis
3.1.4.3 NPC6
-
 Arabidopsis thaliana
3.1.4.3 PC-PLC
-
 Pseudomonas fluorescens
3.1.4.3 PC-PLC
-
 Bacillus cereus
3.1.4.3 PC-PLC
-
 Clostridium perfringens
3.1.4.3 PC-PLC
-
 Ureaplasma urealyticum
3.1.4.3 phosphatidylcholine-specific phospholipase C
-
 Pseudomonas fluorescens
3.1.4.3 phosphatidylcholine-specific phospholipase C
-
 Bacillus cereus
3.1.4.3 phosphatidylcholine-specific phospholipase C
-
 Clostridium perfringens
3.1.4.3 phosphatidylcholine-specific phospholipase C
-
 Ureaplasma urealyticum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.3 additional information
-
 broad pH optimum Ureaplasma urealyticum

Expression

EC Number Organism Comment Expression
3.1.4.3 Arabidopsis thaliana the enzyme is induced by 24-epibrassinolide signalling, auxin, and cytokinin. Expression level of NPC3 is increased 14.6fold after 2 h in seedlings subjected to 37°C heat stress. NPC3 does demonstrate a positive response to Botrytis cinerea, Golovinomyces orontii, Pseudomonas syringae and Phytophthora infestans treatment up
3.1.4.3 Arabidopsis thaliana the enzyme is induced by phosphate deficiency up

General Information

EC Number General Information Comment Organism
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Nicotiana tabacum
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Glycine max
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Sorghum bicolor
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Oryza sativa
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Petunia x hybrida
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Physcomitrium patens
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Vitis vinifera
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Populus trichocarpa
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Picea sitchensis
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Selaginella moellendorffii
3.1.4.3 evolution the enzyme belongs to the plant non-specific phospholipase C gene family, phylogenetic tree, overview. The common ancestor of all seed plants already had at least one NPC1-, NPC2- and NPC6-like gene. Non-specific phospholipases C are a distinct type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C Arabidopsis thaliana
3.1.4.3 malfunction npc4 knockout mutants are characterised by a reduced germination rate when sown on media containing 150 mM NaCl. Mutant npc4 plants also have reduced germination and overall viability under salt and drought stress conditions. Unlike wild-type plants, mutants overexpressing NPC4 are characterised by a higher germination level and maintain a greater root length and dry weight under both salt stress and hyperosmosis Arabidopsis thaliana
3.1.4.3 malfunction the N-terminal domain of a-toxin retains PC-PLC activity when expressed in Escherichia coli, but lacks haemolytic and sphingomyelinase activities that are supposedly granted by a lipoxygenase-like C-terminal domain Clostridium perfringens
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Nicotiana tabacum
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Glycine max
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Sorghum bicolor
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Oryza sativa
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Petunia x hybrida
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Physcomitrium patens
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Vitis vinifera
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Populus trichocarpa
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Picea sitchensis
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Selaginella moellendorffii
3.1.4.3 metabolism model of metabolism regulation carried out by plant cell phospholipases, overview Arabidopsis thaliana
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Nicotiana tabacum
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Glycine max
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Sorghum bicolor
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Oryza sativa
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Petunia x hybrida
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Physcomitrium patens
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Vitis vinifera
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Populus trichocarpa
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Picea sitchensis
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Selaginella moellendorffii
3.1.4.3 additional information sequence comparisons and three-dimensional structure modeling, overview Arabidopsis thaliana
3.1.4.3 additional information the N-terminal domain contains the phospholipase C active site, which also incorporates zinc ions. The C-terminal C2-like PLAT (polycystin-1, lipoxygenase, alpha-toxin) domain was found to be similar to lipid binding domains in eukaryotes and appears to be responsible for binding membrane phospholipids in a calcium-dependent manner Clostridium perfringens
3.1.4.3 physiological function NPC3 might play a rolei in thermotolerance. The enzyme is responsible for lipid conversion during phosphate-limiting conditions. Two articles non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview, inducible expression and putative signalling role Arabidopsis thaliana
3.1.4.3 physiological function NPC4 participates in triggering plant salt stress responses likely via abscisic acid-dependent mechanisms. The enzyme is responsible for lipid conversion during phosphate-limiting conditions. Two articles non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview, inducible expression and putative signalling role Arabidopsis thaliana
3.1.4.3 physiological function the enzyme inhibits the formation of cAMP by adenylate cyclase and is involved in the defence mechanism of bacteria to phagocytosis Bacillus cereus
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Glycine max
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Sorghum bicolor
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Oryza sativa
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Petunia x hybrida
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Physcomitrium patens
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Vitis vinifera
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Populus trichocarpa
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Picea sitchensis
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Selaginella moellendorffii
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Two articles non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Nicotiana tabacum
3.1.4.3 physiological function the enzyme is responsible for lipid conversion during phosphate-limiting conditions. Two articles non-specific phospholipases C are involved in biotic and abiotic stress responses as well as phytohormone actions. The diacylglycerol produced via the enzymes is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. Mode of action of the enzyme in lipid metabolism, signal transduction, and membrane remodelling, detailed overview Arabidopsis thaliana
3.1.4.3 physiological function the secreted enzyme plays a role in the aggregation of blood platelets and inhibits defensive superoxide generation in human polymorphonuclear leukocytes by interacting with membrane components of NADPH oxidase Clostridium perfringens