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Literature summary extracted from

  • Gupta, P.; Jain, M.; Sarangthem, J.; Gadre, R.
    Inhibition of 5-aminolevulinic acid dehydratase by mercury in excised greening maize leaf segments (2013), Plant Physiol. Biochem., 62, 63-69.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.24 5,5'-dithio(bis-2-nitrobenzoic acid)
-
 Zea mays
4.2.1.24 Hg2+ the inhibition caused by 0.37 mM Hg2+ is alleviated by addition of 10 mM KNO3. 10 mM NH4Cl and 5 mM sucrose increase the inhibitory effect of Hg2+ on enzyme activity, while 10 mM levulinic acid and 0.0001 mM 5,5'-dithio(bis-2-nitrobenzoic acid) glutamine and glutathione decrease it Zea mays
4.2.1.24 levulinic acid competitive inhibitor, 8% residual activity at 20 mM Zea mays

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.24 0.347
-
 5-aminolevulinate in the presence of Hg2+, at pH 8.2 and 37°C Zea mays
4.2.1.24 0.532
-
 5-aminolevulinate in the absence of Hg2+, at pH 8.2 and 37°C Zea mays

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.24 5-aminolevulinate Zea mays
-
 porphobilinogen + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.24 Zea mays
-
 cultivar GSF-2
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.24 leaf
-
 Zea mays
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.24 5-aminolevulinate
-
 Zea mays porphobilinogen + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.24 5-aminolevulinic acid dehydratase
-
 Zea mays
4.2.1.24 ALAD
-
 Zea mays