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Literature summary extracted from
- Dammarenediol-II production confers TMV tolerance in transgenic tobacco expressing Panax ginseng dammarenediol-II synthase (2012), Plant Cell Physiol., 53, 173-182.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 4.2.1.125 | gene PgDDS, functional expression in Nicotiana tabacum cv. Xanthi leaves using Agrobacterium strain GV3101, the heterologous expression confers resistance to Tobacco mosaic virus. Expression profile of PgDDS trangenic tobacco plants, overview. Production of dammarenediol-II in transgenic tobacco stimulates the expression of tobacco pathogenesis-related genes (PR1 and PR2) under both virus-untreated and -treated conditions | Panax ginseng |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.125 | (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O | Panax ginseng | dammarenediol-II is a ginsenoside precursor | dammarenediol II | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.125 | Panax ginseng | Q08IT1 | gene PgDDS | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.2.1.125 | root | - |
Panax ginseng | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.125 | (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O | - |
Panax ginseng | dammarenediol II | GC-MS product analysis | ? | |
| 4.2.1.125 | (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O | dammarenediol-II is a ginsenoside precursor | Panax ginseng | dammarenediol II | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.1.125 | dammarenediol-II synthase | - |
Panax ginseng |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 4.2.1.125 | metabolism | the enzyme catalyzes the first step in the synthesis of dammarane-type ginsenoside, the cyclization of 2,3-oxidosqualene to dammarenediol-II, overview | Panax ginseng |
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Release 2023.1 (January 2023)
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