Literature summary extracted from

Monteiro, C.; Fang, X.; Ahmad, I.; Gomelsky, M.; Roemling, U.
Regulation of biofilm components in Salmonella enterica serovar Typhimurium by lytic transglycosylases involved in cell wall turnover (2011), J. Bacteriol., 193, 6443-6451.

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.2.B6	Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Synonyms

EC Number	Synonyms	Comment	Organism
4.2.2.B6	MltE	-	Salmonella enterica subsp. enterica serovar Typhimurium

General Information

EC Number	General Information	Comment	Organism
4.2.2.B6	physiological function	lytic transglycosylases, MltE and MltC, in combination increase transcriptional regulator CsgD expression and distinct colony morphotype on Congo red agar plates, named rdar. MltE and MltC work redundantly to regulate transcriptional regulator CsgD at the transcriptional and posttranscriptional levels. The effect of MltE and MltC on CsgD levels is independent of the known regulatory pathways that sense cell envelope stress. The mltE deletion mutant does not show a change in rdar morphotype expression. The overexpression of MltE from a plasmid leads to an upregulated rdar morphotype after 17 h, and upon extended incubation it manifests as an extended matrix structure on Congo red agar plates	Salmonella enterica subsp. enterica serovar Typhimurium

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Release 2023.1 (January 2023)