EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.B43 | (N6-thiosuccinyl)KSTGGKA | - |
Homo sapiens | |
2.3.1.B43 | Ac-AR(N6-thiosuccinyl)KST-NH2 | - |
Homo sapiens | |
2.3.1.B43 | Ac-RR(N6-thiosuccinyl)KRR-NH2 | - |
Homo sapiens | |
2.3.1.B43 | AGK2 | 40% inhibition at 0.1 mM | Homo sapiens | |
2.3.1.B43 | AR(N6-thiosuccinyl)KST | - |
Homo sapiens | |
2.3.1.B43 | KQTAR(N6-thiosuccinyl)K | - |
Homo sapiens | |
2.3.1.B43 | KQTAR(N6-thiosuccinyl)KSTGGKA | - |
Homo sapiens | |
2.3.1.B43 | additional information | H3K9TAc and sirtinol show no inhibnition at 0.1 mM | Homo sapiens | |
2.3.1.B43 | nicotinamide | - |
Homo sapiens | |
2.3.1.B43 | suramin | - |
Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.B43 | Homo sapiens | Q9NXA8 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.B43 | NAD+ + KQTAR(N6-succinyl)KSTGGKA | - |
Homo sapiens | nicotinamide + KQTARKSTGGKA + 2'-O-succinyl-ADP-ribose | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.B43 | SIRT5 | - |
Homo sapiens |
2.3.1.B43 | sirtuin 5 | - |
Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.3.1.B43 | 0.001 | - |
pH and temperature not specified in the publication | Homo sapiens | KQTAR(N6-thiosuccinyl)K | |
2.3.1.B43 | 0.001 | - |
pH and temperature not specified in the publication | Homo sapiens | (N6-thiosuccinyl)KSTGGKA | |
2.3.1.B43 | 0.005 | - |
pH and temperature not specified in the publication | Homo sapiens | KQTAR(N6-thiosuccinyl)KSTGGKA | |
2.3.1.B43 | 0.025 | - |
pH and temperature not specified in the publication | Homo sapiens | suramin | |
2.3.1.B43 | 0.025 | - |
pH and temperature not specified in the publication | Homo sapiens | Ac-RR(N6-thiosuccinyl)KRR-NH2 | |
2.3.1.B43 | 0.03 | - |
pH and temperature not specified in the publication | Homo sapiens | AR(N6-thiosuccinyl)KST | |
2.3.1.B43 | 0.04 | - |
pH and temperature not specified in the publication | Homo sapiens | Ac-AR(N6-thiosuccinyl)KST-NH2 | |
2.3.1.B43 | 0.15 | - |
pH and temperature not specified in the publication | Homo sapiens | nicotinamide |