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Literature summary extracted from
- Effect of cation-pi interactions and steric bulk on the catalytic action of oxidosqualene cyclase: a case study of Phe728 of beta-amyrin synthase from Euphorbia tirucalli L (2013), Chemistry, 19, 17150-17158.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 5.4.99.39 | F728A | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| 5.4.99.39 | F728H | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| 5.4.99.39 | F728I | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| 5.4.99.39 | F728M | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| 5.4.99.39 | F728W | highly reduced activity compared to wild-type | Euphorbia tirucalli |
| 5.4.99.39 | F728Y | activity comparable to wild-type | Euphorbia tirucalli |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.99.39 | Euphorbia tirucalli | Q401R6 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.39 | (S)-2,3-oxidosqualene | - |
Euphorbia tirucalli | beta-amyrin | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.4.99.39 | amyrin synthase | - |
Euphorbia tirucalli |
| 5.4.99.39 | EtAS | - |
Euphorbia tirucalli |
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Release 2023.1 (January 2023)
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