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Literature summary extracted from

  • Arai, M.; Nihonmatsu-Kikuchi, N.; Itokawa, M.; Rabbani, N.; Thornalley, P.J.
    Measurement of glyoxalase activities (2014), Biochem. Soc. Trans., 42, 491-494.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.4.1.5 cytosol
-
 Mammalia 5829
-

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.5 Mammalia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.5 glutathione + methylglyoxal glyoxalase I catalyses the isomerization of the hemithioacetal formed non-enzymatically from methylglyoxal and glutathione to S-D-lactoylglutathione Mammalia (R)-S-lactoylglutathione
-
 ?
4.4.1.5 additional information spectrophotometric measurement of enzyme activity in tissue and cell culture, modified for use with a UV-transparent microplate for higher sample throughput, method, overview Mammalia ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.5 glyoxalase I
-
 Mammalia

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.4.1.5 37
-
 assay at Mammalia

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.4.1.5 6.6
-
 assay at Mammalia