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Literature summary extracted from

  • Chakraborty, N.; Ghosh, R.; Ghosh, S.; Narula, K.; Tayal, R.; Datta, A.; Chakraborty, S.
    Reduction of oxalate levels in tomato fruit and consequent metabolic remodeling following overexpression of a fungal oxalate decarboxylase (2013), Plant Physiol., 162, 364-378.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.2 gene FvOXDC, recombinant expression in Solanum lycopersicum fruits under the control of a fruit-specific promoter E8.2 being active upon ethylene induction only in ripening fruits, via Agrobacterium tumefaciens-mediated transformation, OXDC is targeted to the cell vacuole in the transgenic fruits. The transgenic fruits show up to a 90% reduction in oxalate content, which correlates with concomitant increases in calcium, iron, and citrate, compared to wild-type fruits. Expression of OXDC affects neither CO2 assimilation rates nor results in any detectable morphological differences in the transgenic plants. OXDC-responsive proteins involved in metabolism and stress responses represent the most substantially up- and down-regulated categories, respectively, in the transgenic fruit, compared with those of wild-type plants, proteome analysis, overview Flammulina velutipes

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.2 oxalate + H+ Flammulina velutipes
-
formate + CO2
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.2 Flammulina velutipes
-
-
-
4.1.1.2 no activity in Solanum lycopersicum
-
in fruits
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.2 oxalate + H+
-
Flammulina velutipes formate + CO2
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.2 FvOXDC
-
Flammulina velutipes
4.1.1.2 OXDC
-
Flammulina velutipes

General Information

EC Number General Information Comment Organism
4.1.1.2 evolution oxalate decarboxylase belongs to the low-pH-inducible cupin superfamily of enzymes Flammulina velutipes